Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021970 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL5089520 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL8704299 | 0.81 | MTNR1A (0.43) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL27953190 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBLMNAUSP2 | |
| Ethylamine SCHEMBL28630883 | 0.77 | TSHR (0.42) | ALDH1A1KMT2ASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL6203162 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAUSP2KMT2A | |
| SCHEMBL2793164 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBLMNAUSP2 | |
| SCHEMBL11754044 | 0.75 | KDM4E (0.54) | ALDH1A1KDM4ELMNAUSP2KMT2A | |
| SCHEMBL11670227 | 0.73 | POLB (0.45) | ALDH1A1KDM4EPOLBLMNAUSP2 | |
| SCHEMBL11670225 | 0.73 | KMT2A (0.44) | ALDH1A1KDM4EPOLBLMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998045260-A1 | PROCESS FOR STEREOSELECTIVE PREPARATION OF AZETIDINONES | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1998-10-15 | — | — | WO | disclosed |