Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167565 | 0.74 | RAB9A (0.57) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL2939268 | 0.73 | HPGD (0.64) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL14939070 | 0.72 | KDM4E (0.66) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL16581342 | 0.71 | KDM4E (0.64) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL13116807 | 0.70 | KDM4E (0.62) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL698939 | 0.70 | MAPT (0.64) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL2749129 | 0.70 | NPC1 (0.66) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL2481124 | 0.70 | KDM4E (0.62) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL231307 | 0.70 | KDM4E (0.75) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL28303204 | 0.70 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981883-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOTHIAZOLES | AstraZeneca AB (SE) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007086800-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOTHIAZOLES | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |