SCHEMBL5090299

SCHEMBL5090299

CCO[Si](C)(CN(C)C1CCCCC1)OCC

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
ALDH1A1 P00352 3/20 0.33
ADH1A P07327 3/20 0.32
ADH1C P00326 2/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MAPK1 P28482 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4326193 0.83 ADH1A (0.33) ALDH1A1ADH1AADH1C
SCHEMBL4344034 0.83 HRH4 (0.37) HRH4HRH3ALDH1A1ADH1AADH1C
SCHEMBL2925347 0.83 ADH1A (0.33) ALDH1A1ADH1AADH1C
SCHEMBL4003379 0.80 ADH1A (0.32) ADH1AADH1C
SCHEMBL15360364 0.79 ADH1C (0.31) ADH1AADH1C
SCHEMBL18138492 0.76 ADH1A (0.33) ALDH1A1ADH1AADH1C
SCHEMBL20461265 0.75 ALDH1A1 (0.39) ALDH1A1KDM4EL3MBTL1MEN1KMT2A
SCHEMBL15360888 0.75
SCHEMBL15360708 0.75
SCHEMBL2925346 0.73 ALDH1A1 (0.39) ALDH1A1ADH1AADH1CTSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080107815-A1 Preparation Of Aqueous Dispersions Of Organopolysiloxanes WACKER CHEMIE AG (DE) 2008-05-08 US disclosed
US-20060258820-A1 Process for preparing dispersions of crosslinked organopolysiloxanes WACKER CHEMIE AG (DE) 2006-11-16 US disclosed