Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25612616 | 0.91 | TSHR (0.56) | TAS1R3TAS1R1CA1CA2SLC6A2 | |
| SCHEMBL828610 | 0.90 | TSHR (0.51) | TAS1R3TAS1R1CA1CA2SLC6A2 | |
| SCHEMBL14094388 | 0.87 | CA1 (0.56) | CA1CA2TSHRPOLBMAPT | |
| SCHEMBL25953791 | 0.85 | PDCD1 (0.54) | CA1CA2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9058141 | 0.85 | PDCD1 (0.54) | CA1CA2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9154263 | 0.84 | TSHR (0.49) | TAS1R3TAS1R1CA1CA2SLC6A2 | |
| SCHEMBL20354073 | 0.83 | ALDH1A1 (0.51) | TSHRMAPTMEN1NPC1KMT2A | |
| SCHEMBL12475416 | 0.83 | ALDH1A1 (0.51) | TSHRMAPTMEN1NPC1KMT2A | |
| SCHEMBL17882060 | 0.83 | L3MBTL1 (0.52) | CA1CA2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8970835 | 0.83 | CA12 (0.62) | CA1CA2SLC6A2SLC6A3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435333-B2 | Photo-switchable membrane and method | UNIVERSITY OF ROCHESTER (US) | 2013-05-07 | — | — | US | disclosed |
| US-20120025136-A1 | PHOTO-SWITCHABLE MEMBRANE AND METHOD | UNIVERSITY OF ROCHESTER (US) | 2012-02-02 | — | — | US | disclosed |