SCHEMBL509164

SCHEMBL509164

C=C(C)C1=NC2(CCCC2)C(=O)O1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL508492 0.98 ALDH1A1 (0.33) ALDH1A1CYP3A4
SCHEMBL508723 0.73
SCHEMBL2571098 0.68
SCHEMBL14085362 0.67 ALDH1A1 (0.39) ALDH1A1CYP3A4
SCHEMBL3327615 0.67 ALDH1A1 (0.36) ALDH1A1CYP3A4
SCHEMBL9168609 0.67
SCHEMBL1842569 0.66 ALDH1A1 (0.43) ALDH1A1CYP3A4
SCHEMBL9864935 0.66 ALDH1A1 (0.35) ALDH1A1CYP3A4
SCHEMBL10412331 0.66
SCHEMBL19790062 0.66 ALDH1A1 (0.38) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313567-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-02-07 EP claimed
EP-4304842-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
EP-4304843-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
US-11833771-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2023-12-05 US claimed
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
EP-4158392-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-04-05 EP claimed
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses ALCON INC. (CH) 2023-02-21 US claimed
WO-2022189941-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-09-15 WO claimed
US-20220281193-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES ALCON INC. (CH) 2022-09-08 US claimed
US-20210371731-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2021-12-02 US claimed
US-5408002-A Blending with thermoplastic polymers; medical diagnostic equipment MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-18 US claimed
WO-1993025594-A1 SUPPORTS HAVING AZLACTONE-FUNCTIONAL SURFACES, ADDUCT SUPPORTS, AND METHODS OF PREPARING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-12-23 WO claimed
US-5262484-A Free radical grafting to addition polymers; surface treatment with nucleophilic agents; adhesion properties for binding, immobilizing proteins; immunoassay MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US claimed
EP-0367583-B1 FLUORINATED, ACRYLAMIDE-FUNCTIONAL MONOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-04 EP claimed
US-5075352-A Stabilized polymeric dispersions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-24 US claimed
US-5013795-A Azlactone graft copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-05-07 US claimed
EP-0413551-A2 Stabilized polymeric dispersions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-20 EP claimed
EP-0367583-A2 Fluorinated, acrylamide-functional monomers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-09 EP claimed
US-4451619-A COPOLYMERIZING AN ALKENYLAZLACTONE, RING OPENING WITH NUCLEOPHILE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-05-29 US claimed
EP-0105666-A1 Method of hydrophilizing or hydrophobizing polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-04-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses COIL, CRYAB, CRYAA ALDH1A1 3383/4885CYP3A4 1161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.