SCHEMBL5094569

SCHEMBL5094569

[N-]=[N+]=C1CC=CC2=C1C(=O)c1ccccc12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
CDC25B P30305 1/20 0.34
MAPT P10636 9/20 0.34
ALDH1A1 P00352 7/20 0.34
SMN1; SMN2 Q16637 6/20 0.34
TP53 P04637 3/20 0.34
MAPK10 P53779 3/20 0.34
PKM P14618 3/20 0.34
GAA P10253 3/20 0.34
GLA P06280 1/20 0.34
KLF5 Q13887 1/20 0.34
NPC1 O15118 6/20 0.33
RAB9A P51151 6/20 0.33
NPSR1 Q6W5P4 3/20 0.33
LMNA P02545 2/20 0.33
RECQL P46063 2/20 0.33
S100A4 P26447 2/20 0.33
APAF1 O14727 2/20 0.33
TDP2 O95551 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4238710 0.94 MEN1 (0.34) MEN1KMT2ACDC25BMAPTALDH1A1
Hydrochloric Acid SCHEMBL11335869 0.91 SMN1; SMN2 (0.33) MEN1KMT2ACDC25BMAPTALDH1A1
SCHEMBL10721373 0.81 MAPT (0.32) MAPTALDH1A1KDM4E
SCHEMBL1501865 0.78 CDC25B (0.41) MEN1KMT2ACDC25BMAPTALDH1A1
SCHEMBL3829679 0.74
SCHEMBL5494021 0.70 CDC25B (0.41) MEN1KMT2ACDC25BMAPTALDH1A1
SCHEMBL10900576 0.70 MAOA (0.36) MEN1KMT2ACDC25BMAPTSMN1; SMN2
SCHEMBL1665655 0.68 CYP2D6 (0.33) MEN1KMT2AMAPTALDH1A1TP53
SCHEMBL28829617 0.68 MAOA (0.36) MEN1KMT2ACDC25BMAPTSMN1; SMN2
SCHEMBL30407019 0.68 CDC25B (0.38) MEN1KMT2ACDC25BMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7444012-B2 Method and apparatus for performing failure analysis with fluorescence inks FREESCALE SEMICONDUCTOR, INC. (US) 2008-10-28 US disclosed
US-20050018898-A1 Method and apparatus for performing failure analysis with fluorescence inks NXP, B.V. F/K/A FREESCALE SEMICONDUCTOR, INC. (NL) 2005-01-27 US disclosed