Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12593305 | 0.90 | ALDH1A1 (0.36) | CRHR1KDM4EMEN1MAPK1HTT | |
| SCHEMBL12535188 | 0.88 | CRHR1 (0.33) | CRHR1KDM4EMEN1MAPK1HTT | |
| SCHEMBL12593352 | 0.88 | CRHR1 (0.36) | CRHR1KDM4EMEN1MAPK1HTT | |
| SCHEMBL1638150 | 0.87 | CRHR1 (0.34) | CRHR1KDM4EMEN1MAPK1HTT | |
| SCHEMBL1638385 | 0.87 | CRHR1 (0.33) | CRHR1KDM4EMEN1MAPK1HTT | |
| SCHEMBL1637194 | 0.85 | CRHR1 (0.33) | CRHR1KDM4EMEN1MAPK1HTT | |
| SCHEMBL12535258 | 0.84 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL1638552 | 0.84 | JAK2 (0.35) | CRHR1 | |
| SCHEMBL1762558 | 0.83 | FFAR4 (0.40) | — | |
| SCHEMBL1638140 | 0.83 | CYP11B2 (0.35) | CRHR1KDM4EMEN1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467997-B8 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP | TAISHO PHARMACEUTICAL CO LTD (JP) | 2008-08-27 | — | — | EP | claimed |
| EP-1467997-A1 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-20 | — | — | EP | claimed |
| WO-2004058767-A1 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-15 | — | — | WO | claimed |