SCHEMBL50970

SCHEMBL50970

Cc1ccc(C(c2ccccc2)c2ccc(C)cc2O)c(O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.57
LMNA P02545 2/20 0.57
CHRM1 P11229 2/20 0.57
ADRA1A P35348 2/20 0.57
SLC6A2 P23975 1/20 0.57
HTR2B P41595 1/20 0.57
KMT2A Q03164 3/20 0.50
HTT P42858 3/20 0.50
MEN1 O00255 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
ALDH1A1 P00352 1/20 0.50
TYR P14679 1/20 0.49
MAPT P10636 2/20 0.44
ESR1 P03372 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
KCNE1 P15382 1/20 0.44
CHRM3 P20309 1/20 0.44
PTGS1 P23219 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979244 0.96 TRPA1 (0.57) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL1758427 0.90 TRPA1 (0.63) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL11954775 0.89 LMNA (0.57) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL51095 0.85 CHRM1 (0.55) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL28296896 0.84 CHRM1 (0.43) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL7012899 0.83 CHRM1 (0.55) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL10411971 0.83 TYR (0.71) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL29209449 0.82 CHRM1 (0.41) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL14676983 0.81 LMNA (0.53) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL28499022 0.81 CHRM1 (0.55) TRPA1LMNACHRM1ADRA1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2181853-B1 Thermosensitive recording medium JUJO PAPER CO LTD (JP) 2015-09-23 EP disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-8129307-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-03-06 US disclosed
US-20110269622-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2011-11-03 US disclosed
US-20110130281-A1 THERMOSENSITIVE RECORDING MEDIUM API CORPORATION 2011-06-02 US disclosed
EP-2112001-B1 THERMOSENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2011-05-11 EP disclosed
EP-2261045-A1 HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2010-12-15 EP disclosed
EP-2181853-A1 THERMAL RECORDING MATERIAL Nippon Paper Industries Co., Ltd. (JP) 2010-05-05 EP disclosed
US-20100099557-A1 Thermosensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-04-22 US disclosed
EP-1437231-B1 DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS API CORP (JP) 2008-01-09 EP disclosed
US-20040241598-A1 Developer for thermal recording material and thermal recording materials NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-12-02 US disclosed
EP-1437231-A1 DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS API Corporation (JP) 2004-07-14 EP disclosed