SCHEMBL8979244

SCHEMBL8979244

Cc1ccc(C(c2ccccc2)c2ccccc2)c(O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.57
LMNA P02545 2/20 0.57
CHRM1 P11229 2/20 0.57
ADRA1A P35348 2/20 0.57
SLC6A2 P23975 1/20 0.57
HTR2B P41595 1/20 0.57
KMT2A Q03164 3/20 0.50
HTT P42858 3/20 0.50
MEN1 O00255 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
ALDH1A1 P00352 1/20 0.50
TYR P14679 1/20 0.49
MAPT P10636 2/20 0.44
ESR1 P03372 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
KCNE1 P15382 1/20 0.44
CHRM3 P20309 1/20 0.44
PTGS1 P23219 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50970 0.96 TRPA1 (0.57) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL1758427 0.86 TRPA1 (0.63) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL11954775 0.85 LMNA (0.57) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL28499022 0.85 CHRM1 (0.55) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL7012899 0.83 CHRM1 (0.55) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL10411971 0.83 TYR (0.71) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL14676983 0.81 LMNA (0.53) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL28296896 0.81 CHRM1 (0.43) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL51095 0.81 CHRM1 (0.55) TRPA1LMNACHRM1ADRA1ASLC6A2
SCHEMBL11410686 0.80 CACNA2D1 (0.43) LMNASLC6A2KMT2AHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115541771-B Method for detecting impurities of 2-benzhydryl-5-methylphenol and benzophenone hydrazone in tazobactam 海南通用三洋药业有限公司 2024-08-30 CN claimed
CN-115541771-A Method for detecting 2-benzhydryl-5-methylphenol and benzophenone hydrazone impurities in tazobactam 海南通用三洋药业有限公司 2022-12-30 CN claimed
CN-115541771-B Method for detecting impurities of 2-benzhydryl-5-methylphenol and benzophenone hydrazone in tazobactam 海南通用三洋药业有限公司 2024-08-30 CN disclosed
CN-115541771-B Method for detecting impurities of 2-benzhydryl-5-methylphenol and benzophenone hydrazone in tazobactam 海南通用三洋药业有限公司 2024-08-30 CN disclosed
CN-115541771-B Method for detecting impurities of 2-benzhydryl-5-methylphenol and benzophenone hydrazone in tazobactam 海南通用三洋药业有限公司 2024-08-30 CN disclosed
US-20240025873-A1 METHOD FOR PRODUCING KETONE DERIVATIVE TOKUYAMA CORPORATION (JP) 2024-01-25 US disclosed
EP-4249462-A1 METHOD FOR PRODUCING KETONE DERIVATIVE Tokuyama Corporation (JP) 2023-09-27 EP disclosed
CN-115541771-A Method for detecting 2-benzhydryl-5-methylphenol and benzophenone hydrazone impurities in tazobactam 海南通用三洋药业有限公司 2022-12-30 CN disclosed
CN-115541771-A Method for detecting 2-benzhydryl-5-methylphenol and benzophenone hydrazone impurities in tazobactam 海南通用三洋药业有限公司 2022-12-30 CN disclosed
CN-115541771-A Method for detecting 2-benzhydryl-5-methylphenol and benzophenone hydrazone impurities in tazobactam 海南通用三洋药业有限公司 2022-12-30 CN disclosed
EP-0536710-B1 Amino acid derivatives for peptide synthesis BACHEM FEINCHEMIKALIEN AG (CH) 1996-05-08 EP disclosed
US-5455363-A Having trityl as amide-protecting group for asparagine and glutamine; reduced side reaction GOSTELI JACQUES (CH) 1995-10-03 US disclosed
EP-0536710-A1 Amino acid derivatives for peptide synthesis BACHEM FEINCHEMIKALIEN AG (CH) 1993-04-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025873-A1 METHOD FOR PRODUCING KETONE DERIVATIVE HSD17B7, BCKDK, KARS1 TRPA1 3574/4885LMNA 3073/4885CHRM1 4477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.