Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090836 | 0.87 | LMNA (0.41) | HPGDHDAC6LMNAHDAC3HDAC4 | |
| SCHEMBL5090684 | 0.85 | ALDH1A1 (0.39) | HPGDHDAC6LMNAHDAC3HDAC4 | |
| SCHEMBL5139867 | 0.85 | HDAC3 (0.50) | HPGDHDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL5134813 | 0.76 | HDAC3 (0.42) | HDAC6LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL4390392 | 0.73 | KDM4E (0.39) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4390398 | 0.73 | KDM4E (0.39) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5085616 | 0.72 | HPGD (0.40) | HPGDHDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL2007623 | 0.68 | TAAR1 (0.41) | TAAR1 | |
| SCHEMBL5806467 | 0.67 | HDAC3 (0.62) | HDAC6LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL928881 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968609-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HIGHLY LIPOPHILIC SULFHYDRYL COMPOUNDS | RND Pharmaceuticals, Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007073560-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HIGHLY LIPOPHILIC SULFHYDRYL COMPOUNDS | RND PHARMACEUTICALS, INC. (US) | 2007-06-28 | — | — | WO | disclosed |