Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034148 | 0.79 | SLC6A2 (0.46) | SLC6A3CHRM2CHRM1CHRM3HSD11B1 | |
| Hydrochloric Acid SCHEMBL6498978 | 0.79 | SLC6A4 (0.52) | SLC6A3CA12CA1CA9CHRM2 | |
| SCHEMBL3062717 | 0.77 | SLC6A4 (0.53) | SLC6A3CA12CA1CA9CHRM2 | |
| Cadaverine Tartrate SCHEMBL3542909 | 0.77 | SLC6A3 (0.48) | SLC6A3CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL18043583 | 0.76 | SLC6A2 (0.41) | SLC6A3CHRM2CHRM1CHRM3WDR5 | |
| SCHEMBL3061088 | 0.75 | CHRM2 (0.40) | SLC6A3CA12CA1CA9CHRM2 | |
| SCHEMBL2071693 | 0.74 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL31412599 | 0.73 | ACKR3 (0.48) | MMP13ACKR3SLC6A3CA12CA1 | |
| SCHEMBL6491111 | 0.73 | GPR119 (0.46) | CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL12094592 | 0.73 | GPR119 (0.46) | CHRM2CHRM1CHRM3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314870-B2 | Compounds, their preparation and use | NEUROSEARCH A/S (DK) | 2008-01-01 | — | — | US | disclosed |
| EP-1406900-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | NEUROSEARCH AS (DK) | 2006-10-04 | — | — | EP | disclosed |
| US-20040180877-A1 | Novel compounds, their preparation and use | ANIONA APS (DK) | 2004-09-16 | — | — | US | disclosed |
| EP-1406900-A1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003004493-A1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180877-A1 | Novel compounds, their preparation and use | CHRNA6, CHRNA10, CHRNA5 | MMP13 1197/4885ACKR3 269/4885SLC6A3 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.