SCHEMBL509806

SCHEMBL509806

FC(F)(F)C(CC1([SiH3])CCCCO1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.33
OPRM1 P35372 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4284401 0.78 OPRM1 (0.31) OPRM1
SCHEMBL4533819 0.78 TAAR1 (0.37) OPRM1
SCHEMBL7208915 0.76
SCHEMBL2404032 0.76 ALDH1A1 (0.39) OPRM1
SCHEMBL154897 0.72
SCHEMBL152881 0.72 OPRM1 (0.33) OPRM1
SCHEMBL4991851 0.72 SLC6A2 (0.39) PARP1OPRM1
SCHEMBL19875037 0.71 POLB (0.35) OPRM1
SCHEMBL7055072 0.71 KCNH2 (0.32) OPRM1
SCHEMBL27858266 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9725326-B2 Hydrophilic silica as filler for silicone rubber formulations EVONIK DEGUSSA GMBH (DE) 2017-08-08 US disclosed
US-20120029136-A1 HYDROPHILIC SILICA AS FILLER FOR SILICONE RUBBER FORMULATIONS EVONIK DEGUSSA GMBH (DE) 2012-02-02 US disclosed
US-4208316-A REINFORCING FILLER HARDENABLE ELASTOMERS DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-06-17 US disclosed