SCHEMBL7055072

SCHEMBL7055072

CC([SiH3])(CC1([SiH3])CCCCO1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.32
OPRM1 P35372 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4533819 0.74 TAAR1 (0.37) OPRM1
SCHEMBL7243099 0.72 RIPK1 (0.38) OPRM1
SCHEMBL2404032 0.72 ALDH1A1 (0.39) OPRM1
SCHEMBL152881 0.71 OPRM1 (0.33) KCNH2OPRM1
SCHEMBL4284401 0.71 OPRM1 (0.31) OPRM1
SCHEMBL509806 0.71 PARP1 (0.33) OPRM1
SCHEMBL19875037 0.70 POLB (0.35) KCNH2OPRM1
SCHEMBL7208915 0.69
SCHEMBL28351200 0.69 TAAR1 (0.33) OPRM1
SCHEMBL60702 0.68 MAOA (0.41) KCNH2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863185-B1 Flame retardant additive based on polysiloxane for aromatic polymers GEN ELECTRIC (US) 2003-05-14 EP claimed
US-5955542-A FLAME RETARDANCE ADDITIVE COMPRISING COPOLYMER OF ARYL-CONTAINING SILICONE COMPOUND AND DIORGANIC POLYSILOXANE COMPOUND GENERAL ELECTRIC COMPANY (US) 1999-09-21 US claimed
EP-0863185-B1 Flame retardant additive based on polysiloxane for aromatic polymers GEN ELECTRIC (US) 2003-05-14 EP disclosed
US-5955542-A FLAME RETARDANCE ADDITIVE COMPRISING COPOLYMER OF ARYL-CONTAINING SILICONE COMPOUND AND DIORGANIC POLYSILOXANE COMPOUND GENERAL ELECTRIC COMPANY (US) 1999-09-21 US disclosed
EP-0863185-A2 Flame retardant additive based on polysiloxane for aromatic polymers GENERAL ELECTRIC COMPANY (US) 1998-09-09 EP disclosed