Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PON1 | P27169 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1225503 | 0.89 | KDM4E (0.40) | KMT2AMAPK1KDM4EPON1RAB9A | |
| SCHEMBL3025730 | 0.81 | DHFR (0.36) | KMT2AMAPK1KDM4EALDH1A1GAA | |
| SCHEMBL509442 | 0.80 | HSPA5 (0.35) | KMT2AGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL18966864 | 0.75 | KMT2A (0.40) | KMT2AKDM4EALDH1A1NOS3NOS2 | |
| SCHEMBL1224583 | 0.75 | KMT2A (0.32) | KMT2AMAPK1ALDH1A1GAAHPGD | |
| SCHEMBL27057362 | 0.75 | KMT2A (0.32) | KMT2AMAPK1ALDH1A1GAAHPGD | |
| SCHEMBL508950 | 0.75 | ALDH1A1 (0.38) | KMT2AMAPK1KDM4EALDH1A1GAA | |
| SCHEMBL28343893 | 0.75 | KDM4E (0.33) | KMT2AKDM4E | |
| SCHEMBL811989 | 0.74 | SIGMAR1 (0.38) | KMT2AMAPK1RAB9AALDH1A1GAA | |
| SCHEMBL6915173 | 0.73 | SMN1; SMN2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096106-A | A kind of preparation method of pinoxaden key intermediate | 南京齐正化学有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-109096106-A | A kind of preparation method of pinoxaden key intermediate | 南京齐正化学有限公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-109096106-A | A kind of preparation method of pinoxaden key intermediate | 南京齐正化学有限公司 | 2018-12-28 | — | — | CN | disclosed |
| EP-2334175-B1 | PHENYL-SUBSTITUTED BICYCLOOCTANE 1,3 DIONE DERIVATIVES | BAYER IP GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| CN-102264226-B | Bicyclooctane-1, the 3-derovatives of phenyl-replacement | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-16 | — | — | CN | disclosed |
| US-8507410-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8367873-B2 | Phenyl-substituted bicyclooctane-1,3-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2013-02-05 | — | — | US | disclosed |
| US-8367873-B2 | Phenyl-substituted bicyclooctane-1,3-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2013-02-05 | — | — | US | disclosed |
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2406232-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2012-01-18 | — | — | EP | disclosed |
| CN-102264226-A | Phenyl-substituted bicyclooctane-1,3-dione derivatives | — | 2011-11-30 | — | — | CN | disclosed |
| US-20110039701-A1 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110039701-A1 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| WO-2010104217-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010040460-A2 | PHENYL-SUBSTITUTED BICYCLOOCTANE-1,3-DIONE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039701-A1 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives | DDT, PIP5K1B, PIP5K1C | KMT2A 2664/4885MAPK1 330/4885KDM4E 1388/4885 |
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | C5, C1S, WEE1 | KMT2A 4005/4885MAPK1 714/4885KDM4E 3295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.