Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL107 | 0.82 | — | — | |
| Bromide SCHEMBL3378419 | 0.67 | — | — | |
| Bromide SCHEMBL11006972 | 0.67 | CA4 (0.67) | — | |
| Bromide SCHEMBL11589597 | 0.67 | CA1 (0.33) | — | |
| Bromide SCHEMBL3456702 | 0.67 | — | — | |
| Bromide SCHEMBL6946786 | 0.67 | — | — | |
| Bromide SCHEMBL11339883 | 0.67 | — | — | |
| Bromide SCHEMBL22129188 | 0.67 | — | — | |
| Bromide SCHEMBL10980416 | 0.67 | CA4 (0.67) | — | |
| Bromide SCHEMBL5341109 | 0.67 | CA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465797-B2 | 6-monoacetylmorphine derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-20070191595-A1 | 6-MONOACETYLMORPHINE DERIVATIVES USEFUL IN IMMUNOASSAY | GHOSHAL MITALI | 2007-08-16 | — | — | US | disclosed |
| EP-1810973-A1 | 6-monoacetylmorphine derivatives useful in immunoassay | Roche Diagnostics GmbH (DE) | 2007-07-25 | — | — | EP | disclosed |
| US-7238791-B1 | 6-monoacetylmorphine derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| US-20070142628-A1 | 6-Monoacetylmorphine derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2007-06-21 | — | — | US | disclosed |