Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002413 | 0.82 | LTA4H (0.41) | ALDH1A1TSHRNPC1RAB9ANPSR1 | |
| SCHEMBL28253465 | 0.81 | ESR1 (0.39) | ALDH1A1TSHRLMNAMAPTTP53 | |
| SCHEMBL28253562 | 0.81 | ESR1 (0.39) | ALDH1A1TSHRLMNAMAPTTP53 | |
| SCHEMBL1416128 | 0.81 | — | — | |
| SCHEMBL6003116 | 0.80 | LTA4H (0.41) | ALDH1A1TSHRLMNAMAPTTP53 | |
| SCHEMBL27347287 | 0.79 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL6002127 | 0.79 | TSHR (0.41) | ALDH1A1TSHRLMNAMAPTTP53 | |
| SCHEMBL8351572 | 0.79 | TSHR (0.41) | ALDH1A1TSHRLMNAMAPTTP53 | |
| SCHEMBL28472818 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPTALOX15 | |
| SCHEMBL27778437 | 0.79 | ALOX15 (0.38) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217723-B2 | Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. | EISAI CO., LTD. (JP) | 2007-05-15 | — | — | US | claimed |
| US-20050227959-A1 | Heterocyclic compound having oxime group | EISAI CO., LTD. (JP) | 2005-10-13 | — | — | US | claimed |
| US-4116953-A | 2-PHENYL-3,1-BENZOXAZIN-4-ONES, PIGMENTS | BASF AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | claimed |
| CN-105874879-B | Organic electroluminescent element | 日产化学工业株式会社 | 2018-11-13 | — | — | CN | disclosed |
| CN-105431489-B | Carbon material dispersion membrane formation composition | 日产化学工业株式会社 | 2018-06-08 | — | — | CN | disclosed |
| CN-105980497-A | Protective film forming composition for transparent conductive film | 日产化学工业株式会社 | 2016-09-28 | — | — | CN | disclosed |
| CN-105980496-A | Film-forming composition | 日产化学工业株式会社 | 2016-09-28 | — | — | CN | disclosed |
| CN-105874879-A | Organic electroluminescent element | 日产化学工业株式会社 | 2016-08-17 | — | — | CN | disclosed |
| CN-105431489-A | Carbon material dispersed film formation composition | NISSAN CHEMICAL IND LTD | 2016-03-23 | — | — | CN | disclosed |
| CN-102459415-B | Triazine ring-containing polymer and film-forming composition containing same | NISSAN CHEMICAL IND LTD | 2014-07-02 | — | — | CN | disclosed |
| CN-103429664-A | Photocurable film-forming composition and method for producing cured film | NISSAN CHEMICAL IND LTD | 2013-12-04 | — | — | CN | disclosed |
| CN-1033227-C | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and their use. | SANKYO CO (JP) | 1996-11-06 | — | — | CN | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| CN-1112555-A | Epoxysuccinic acid derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-11-29 | — | — | CN | disclosed |
| CN-1074446-A | Hydroxypyridine Derivatives | SANKYO CO (JP) | 1993-07-21 | — | — | CN | disclosed |
| CN-1072686-A | Has Pyrmidine nucleoside derivatives of anti-tumor activity and its production and use | SANKYO CO (JP) | 1993-06-02 | — | — | CN | disclosed |
| US-4230704-A | BACTERICIDES, FUNGICIDES, ALGICIDES | ROHM AND HAAS COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| US-4169949-A | BACTERICIDES, FUNGICIDES, ANGICIDES, PESTICIDES | ROHM AND HAAS COMPANY (US) | 1979-10-02 | — | — | US | disclosed |
| US-4116953-A | 2-PHENYL-3,1-BENZOXAZIN-4-ONES, PIGMENTS | BASF AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4052371-A | AZO PIGMENT OR DYE HAVING A NAPHTHYL-QUINAZALONE COUPLING COMPONENT | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227959-A1 | Heterocyclic compound having oxime group | STAT6, HRH4, HRH2 | ALDH1A1 1391/4885TSHR 284/4885GLA 2415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.