Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | PLD2 | O14939 | 2/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5102691 | 0.87 | HRH3 (0.50) | CCR3HRH3CARM1PRMT6PLD2 | |
| SCHEMBL5658226 | 0.84 | DRD2 (0.49) | CCR3HRH3CARM1PRMT6HRH1 | |
| SCHEMBL5102255 | 0.80 | CARM1 (0.65) | HRH3CARM1PRMT6 | |
| SCHEMBL7186721 | 0.79 | CARM1 (0.45) | CCR3HRH3CARM1PRMT6HRH1 | |
| SCHEMBL5657642 | 0.78 | L3MBTL1 (0.42) | CCR3HRH3PLD1HRH1GRIN1 | |
| SCHEMBL5655801 | 0.77 | GPR6 (0.49) | CCR3HRH3PLD2PLD1HRH1 | |
| SCHEMBL5099023 | 0.77 | HRH3 (0.44) | CCR3HRH3CARM1PRMT6HRH1 | |
| SCHEMBL5657759 | 0.76 | HRH3 (0.53) | CCR3HRH3OPRD1PLD2PLD1 | |
| SCHEMBL5654782 | 0.76 | CCR3 (0.59) | CCR3HRH3PLD2PLD1HRH1 | |
| SCHEMBL6403503 | 0.76 | CCR3 (0.56) | CCR3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348341-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2008-03-25 | — | — | US | disclosed |
| US-20030166652-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2003-09-04 | — | — | US | disclosed |
| EP-1322611-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-07-02 | — | — | EP | disclosed |
| EP-1289956-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-03-12 | — | — | EP | disclosed |
| WO-2002020484-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-03-14 | — | — | WO | disclosed |
| WO-2001092227-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166652-A1 | Chemical compounds | CCR3, CCR1, CCR4 | CCR3 1/4885HRH3 471/4885CARM1 294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.