⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130287 | 0.85 | — | — | |
| SCHEMBL7629026 | 0.78 | ADRA2A (0.50) | — | |
| SCHEMBL3608336 | 0.74 | — | — | |
| SCHEMBL3608335 | 0.74 | — | — | |
| SCHEMBL19538200 | 0.74 | — | — | |
| SCHEMBL24533674 | 0.73 | — | — | |
| SCHEMBL10143149 | 0.73 | — | — | |
| SCHEMBL19533129 | 0.73 | ADRA2A (0.42) | — | |
| SCHEMBL12870235 | 0.73 | — | — | |
| SCHEMBL4401199 | 0.72 | ADRA2A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7062080-A | — | — | None | — | — | JP | disclosed |
| CN-118206745-A | Compounds and blocking agents comprising the same | 菲鹏生物股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-114426494-B | Substituted methylamine derivatives acting on TAAR agonist | 江苏海洋大学 | 2023-09-15 | — | — | CN | disclosed |
| WO-2022271658-A1 | TRICYCLIC KRAS INHIBITORS | ERASCA, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| US-20220280527-A1 | TRACE AMINE ASSOCIATED RECEPTOR 1 AGONISTS AND PARTIAL AGONISTS FOR PAIN TREATMENT | PURDUE PHARMA L.P. (US) | 2022-09-08 | — | — | US | disclosed |
| CN-114426494-A | Substituted methylamine derivative acting on TAAR agonist | 江苏海洋大学 | 2022-05-03 | — | — | CN | disclosed |
| WO-2021108683-A1 | COVALENT RAS INHIBITORS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2021-06-03 | — | — | WO | disclosed |
| US-20170313708-A1 | NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF | FELIQS CORPORATION (JP) | 2017-11-02 | — | — | US | disclosed |
| US-9790197-B2 | Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient | KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R & D (BE) | 2017-10-17 | — | — | US | disclosed |
| EP-2459542-B1 | Substituted N-benzyl-4,5-dihydrooxazol-2-amines useful as selective alpha 2B/2C receptor agonists | ALLERGAN INC (US) | 2014-10-29 | — | — | EP | disclosed |
| US-6255493-B1 | REACTING IMIDATE ESTER WITH CHIRAL ALCOHOL IN PRESENCE OF TRANSITION METAL CATALYST TO FORM BIS(4-(R)-PHENYLOXAZOLIN-2-YL-METHYL)AMINE LIGANDS; USE TO MAKE RUTHENIUM CATALYST FOR TRANSFER HYDROGENATION | THE PENN STATE RESEARCH FOUNDATION | 2001-07-03 | — | — | US | disclosed |
| EP-1030849-A1 | TRANSITION METAL-CATALYZED REACTIONS BASED ON CHIRAL AMINE OXAZOLINYL LIGANDS | The Pennsylvania State University (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024410-A1 | TRANSITION METAL-CATALYZED REACTIONS BASED ON CHIRAL AMINE OXAZOLINYL LIGANDS | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-05-20 | — | — | WO | disclosed |
| CN-1186494-A | Antibacterial cephalosporins | BIOCHEMIE GMBH (AT) | 1998-07-01 | — | — | CN | disclosed |
| EP-0824535-A1 | ANTIBACTERIAL CEPHALOSPORINS | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035692-A1 | ANTIBACTERIAL CEPHALOSPORINS | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1996-11-14 | — | — | WO | disclosed |
| JP-H0762080-A | PRODUCTION OF POLYCARBONATE RESIN | TEIJIN LTD | 1995-03-07 | — | — | JP | disclosed |
| EP-0030350-B1 | METHOD FOR REDUCING THE TERMINAL CARBOXYL GROUP CONTENT OF A SATURATED POLYESTER, A SATURATED POLYESTER HAVING A REDUCED TERMINAL CARBOXYL GROUP CONTENT, AND A MOLDED ARTICLE COMPOSED OF SUCH A SATURATED POLYESTER | TEIJIN LIMITED (JP) | 1984-10-10 | — | — | EP | disclosed |
| US-4351936-A | COMPRISING ENDCAPPING WITH AN OXAZOLINE OR OXAZINE | TEIJIN LIMITED (JP) | 1982-09-28 | — | — | US | disclosed |
| EP-0030350-A1 | Method for reducing the terminal carboxyl group content of a saturated polyester, a saturated polyester having a reduced terminal carboxyl group content, and a molded article composed of such a saturated polyester | TEIJIN LIMITED (JP) | 1981-06-17 | — | — | EP | disclosed |