SCHEMBL510001

SCHEMBL510001

O=C(CCl)OC(=O)CCCC(=O)OC(=O)CCl

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
ALDH1A1 P00352 1/20 0.43
PRSS1 P07477 1/20 0.32
CTSG P08311 1/20 0.32
CTRB1 P17538 1/20 0.32
CMA1 P23946 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
DGKA P23743 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30483665 0.91 TSHR (0.52) TSHRALDH1A1SLC22A6CYP1A2
SCHEMBL2750422 0.88 ALDH1A1 (0.48) TSHRALDH1A1PRSS1CTSGCTRB1
SCHEMBL4642576 0.85 ALDH1A1 (0.37) TSHRALDH1A1
SCHEMBL16026 0.85
SCHEMBL27904546 0.84 ALDH1A1 (0.52) TSHRALDH1A1DGKA
SCHEMBL27713192 0.82 TSHR (0.41) TSHRALDH1A1
SCHEMBL27705406 0.82 TSHR (0.41) TSHRALDH1A1
SCHEMBL10681686 0.82 DGKA (0.55) TSHRALDH1A1SLC22A6DGKA
SCHEMBL28671993 0.82 DGKA (0.55) TSHRALDH1A1SLC22A6DGKA
SCHEMBL28693155 0.82 DGKA (0.55) TSHRALDH1A1SLC22A6DGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724531-A1 THERMOPLASTIC COMPOSITION, ARTICLES PREPARED THEREFROM, AND METHOD FOR THE MANUFACTURE THEREOF SHPP Global Technologies B.V. (NL) 2026-04-15 EP disclosed
WO-2024252351-A1 THERMOPLASTIC COMPOSITION, ARTICLES PREPARED THEREFROM, AND METHOD FOR THE MANUFACTURE THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-12-12 WO disclosed
WO-2024224178-A1 COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-10-31 WO disclosed
EP-4455197-A1 COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE COMPOSITION SHPP Global Technologies B.V. (NL) 2024-10-30 EP disclosed
CN-115667400-B Composition, method for preparing same, and articles made therefrom 高新特殊工程塑料全球技术有限公司 2024-05-24 CN disclosed
CN-115667400-A Compositions, methods for making the same, and articles made therefrom 高新特殊工程塑料全球技术有限公司 2023-01-31 CN disclosed
CN-114430763-A Non-halogenated flame retardant and reinforced poly (alkylene terephthalate) poly (phenylene ether) compositions, methods of making, and uses thereof 高新特殊工程塑料全球技术有限公司 2022-05-03 CN disclosed
EP-2999765-B1 PROPPANT AND METHOD OF PROPPING A SUBTERRANEAN FRACTURE SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-03-04 EP disclosed
EP-2588656-B1 POLYAMIDE-POLY(ARYLENE ETHER) FIBER AND METHOD FOR ITS PREPARATION SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-01-09 EP disclosed
EP-2563855-B1 THERMALLY INSULATED STRUCTURAL MEMBERS, AND DOORS AND WINDOWS INCORPORATING THEM SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-11-28 EP disclosed
EP-0657498-A1 Thermoplastic composition comprising a compatibilized polyphenylene ether-polyamide base resin, one or more phosphorus compounds GENERAL ELECTRIC COMPANY (US) 1995-06-14 EP disclosed
US-5324782-A Thermoplastic blend with ductility-improving, selectively hydrogenated di-block ethylene-propylene copolymer GENERAL ELECTRIC COMPANY (US) 1994-06-28 US disclosed
US-5248728-A Hydrogenated ethylene-propylene-styrene terpolymer, compatibilizers GENERAL ELECTRIC COMPANY (US) 1993-09-28 US disclosed
EP-0258421-B1 IMPACT MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1992-08-12 EP disclosed
US-4970272-A Polyphenylene ether-polyamide compositions GENERAL ELECTRIC COMPANY (US) 1990-11-13 US disclosed
US-4874810-A BLENDS WITH HYDROGENATED BLOCK POLYMERS OF ETHYLENE, PROPYLENE AND AROMATIC OLEFINS, GLASS FIBERS; HEAT RESISTANCE GENERAL ELECTRIC COMPANY (US) 1989-10-17 US disclosed
EP-0301004-A1 POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1989-02-01 EP disclosed
WO-1988006168-A1 POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1988-08-25 WO disclosed
EP-0258421-A1 IMPACT MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS. GEN ELECTRIC (US) 1988-03-09 EP disclosed
WO-1987005311-A1 IMPACT MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1987-09-11 WO disclosed