Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30407118 | 0.80 | KDM4E (0.35) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28029277 | 0.77 | — | — | |
| SCHEMBL5734597 | 0.76 | — | — | |
| SCHEMBL6852738 | 0.73 | — | — | |
| SCHEMBL13138773 | 0.73 | ABCG2 (0.39) | — | |
| SCHEMBL293044 | 0.72 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1850273 | 0.72 | RORC (0.34) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5665840 | 0.71 | ATM (0.30) | — | |
| SCHEMBL1735849 | 0.70 | ABCG2 (0.32) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL293045 | 0.70 | KDM4E (0.37) | KDM4EMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280290-B1 | AGENT HAVING AN ANTIDEPRESSIVE ACTIVITY | BOEHRINGER INGELHEIM KG (DE) | 1992-01-08 | — | — | EP | claimed |
| US-7410997-B2 | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof | NIPPON SULSAN KAISHA, LTD. (JP) | 2008-08-12 | — | — | US | disclosed |
| EP-1182200-B1 | TRICYCLIC FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR PREPARING THE SAME AND USE THEREOF | NIPPON SUISAN KAISHA LTD (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-20040127713-A1 | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof | NIPPON SUISAN KAISHA, LTD. | 2004-07-01 | — | — | US | disclosed |
| US-6700013-B2 | O-BROMOPHENYLACETIC ACID DERIVATIVE CHEMICAL INTERMEDIATE; SMOOTH MUSCLE RELAXANTS, ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| US-20030220360-A1 | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof | NIPPON SUISAN KAISHA, LTD., A JAPAN CORPORATION | 2003-11-27 | — | — | US | disclosed |
| US-6602898-B1 | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof | NIPPON SUISAN KAISHA, LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1182200-A9 | TRICYCLIC FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Nippon Suisan Kaisha, Ltd. (JP) | 2002-05-22 | — | — | EP | disclosed |
| EP-1182200-A1 | TRICYCLIC FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Nippon Suisan Kaisha, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220360-A1 | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof | HRH2, HRH1, HRH4 | KDM4E 2009/4885MEN1 4301/4885ALDH1A1 899/4885 |
| US-20040127713-A1 | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof | HRH2, HRH1, HRH4 | KDM4E 2009/4885MEN1 4301/4885ALDH1A1 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.