Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506276 | 0.86 | ABCG2 (0.30) | ABCG2 | |
| SCHEMBL30407118 | 0.84 | KDM4E (0.35) | ABCG2HTR2CHTR2BKDM4EMEN1 | |
| SCHEMBL31412834 | 0.83 | CHRNB4 (0.43) | ABCG2 | |
| SCHEMBL29973138 | 0.82 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL1850273 | 0.79 | RORC (0.34) | ABCG2HTR2CHTR2BKDM4EMEN1 | |
| SCHEMBL30912029 | 0.77 | CA2 (0.36) | — | |
| SCHEMBL2400600 | 0.76 | HTR2C (0.36) | HTR2C | |
| SCHEMBL1923837 | 0.76 | HTR2C (0.36) | HTR2C | |
| SCHEMBL1922162 | 0.76 | HTR2C (0.36) | HTR2C | |
| SCHEMBL2399979 | 0.76 | HTR2C (0.36) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2163551-B1 | An improved process for the preparation of nebivolol hydrochloride | CADILA PHARMACEUTICALS LTD (IN) | 2011-11-16 | — | — | EP | disclosed |
| WO-2011131129-A1 | HANGING ORNAMENT WITH HANGING FUNCTION | CHAN KA CHUEN (CN) | 2011-10-27 | — | — | WO | disclosed |