Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 1.00 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918791 | 0.92 | PAX8 (0.86) | PAX8HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL4621081 | 0.85 | PAX8 (0.74) | PAX8HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL21434395 | 0.81 | PAX8 (0.68) | PAX8HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL4977476 | 0.81 | PAX8 (0.68) | PAX8HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL3707219 | 0.80 | PAX8 (0.67) | PAX8HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL25510 | 0.80 | HPRT1 (1.00) | PAX8HPRT1ALDH1A1HSD17B10CYP2A6 | |
| Chrysene SCHEMBL27115 | 0.80 | HPRT1 (1.00) | PAX8HPRT1ALDH1A1HSD17B10CYP2A6 | |
| Chrysene SCHEMBL9786466 | 0.80 | HPRT1 (1.00) | PAX8HPRT1ALDH1A1HSD17B10CYP2A6 | |
| Chrysene SCHEMBL384031 | 0.80 | HPRT1 (1.00) | PAX8HPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL31177955 | 0.80 | HPRT1 (1.00) | PAX8HPRT1ALDH1A1HSD17B10CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834400-B2 | Method for synthesizing dibenzocycloheptane derivatives by series cyclization of free radicals under electrooxidation conditions | ZHEJIANG NORMAL UNIVERSITY (CN) | 2023-12-05 | — | — | US | claimed |
| WO-2023126006-A1 | CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF | 厦门赛诺邦格生物科技股份有限公司 | 2023-07-06 | — | — | WO | claimed |
| CN-115197079-A | Polyethylene glycol lipid and liposome modified by same, pharmaceutical composition containing liposome, preparation and application of pharmaceutical composition | 厦门赛诺邦格生物科技股份有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-115197080-A | Polyethylene glycol lipid and liposome modified by same, pharmaceutical composition containing liposome, preparation and application of pharmaceutical composition | 厦门赛诺邦格生物科技股份有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-115010915-A | Nitrogen branched nine-arm polyethylene glycol derivative, preparation method and biological related substance modified by nitrogen branched nine-arm polyethylene glycol derivative | 厦门赛诺邦格生物科技股份有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-110591079-B | Preparation method of monofunctional nonlinear polyethylene glycol | 厦门赛诺邦格生物科技股份有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-110643032-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-113429559-A | Six-arm polyethylene glycol derivative with end hetero-functionalized and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-113402405-A | Cationic lipid, liposome containing cationic lipid, nucleic acid pharmaceutical composition containing liposome, preparation and application thereof | 厦门赛诺邦格生物科技股份有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-112694608-A | Six-arm polyethylene glycol derivative, preparation method and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2021-04-23 | — | — | CN | claimed |
| US-20040009967-A1 | Pyridyl alkene- and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | KLINGE PHARMA GMBH | 2004-01-15 | — | — | US | claimed |
| US-20030162972-A1 | Pyridyl alkane acid amides as cytostatics and immunosupressives | KLINGE PHARMA GMBH | 2003-08-28 | — | — | US | claimed |
| EP-0799201-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 4-ETHYL-PIPERIDINES | NEUROSEARCH AS (DK) | 2001-09-26 | — | — | EP | claimed |
| JP-2000512652-A | — | — | 2000-09-26 | — | — | JP | claimed |
| EP-0934309-A1 | NEW PYRIDYL ALKANE ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | Klinge Pharma GmbH (DE) | 1999-08-11 | — | — | EP | claimed |
| EP-0923570-A1 | PYRIDYL ALKENE- AND PYRIDYL ALKINE- ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | Klinge Pharma GmbH (DE) | 1999-06-23 | — | — | EP | claimed |
| EP-0912176-A1 | USE OF PYRIDYL ALKANE, PYRIDYL ALKENE AND/OR PYRIDYL ALKINE ACID AMIDES IN THE TREATMENT OF TUMORS OR FOR IMMUNOSUPPRESSION | Klinge Pharma GmbH (DE) | 1999-05-06 | — | — | EP | claimed |
| WO-1997048397-A1 | USE OF PYRIDYL ALKANE, PYRIDYL ALKENE AND/OR PYRIDYL ALKINE ACID AMIDES IN THE TREATMENT OF TUMORS OR FOR IMMUNOSUPPRESSION | KLINGE PHARMA GMBH (DE) | 1997-12-24 | — | — | WO | claimed |
| WO-1997048696-A1 | PYRIDYL ALKENE- AND PYRIDYL ALKINE- ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | KLINGE PHARMA GMBH (DE) | 1997-12-24 | — | — | WO | claimed |
| WO-1997048695-A1 | NEW PYRIDYL ALKANE ACID AMIDES AS CYTOSTATICS AND IMMUNOSUPPRESSIVES | KLINGE PHARMA GMBH (DE) | 1997-12-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009967-A1 | Pyridyl alkene- and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | IDO1, ALK, ARG1 | PAX8 2024/4885HPRT1 172/4885ALDH1A1 173/4885 |
| US-20030162972-A1 | Pyridyl alkane acid amides as cytostatics and immunosupressives | ALK, TYMP, ANXA1 | PAX8 2117/4885HPRT1 198/4885ALDH1A1 168/4885 |
| US-11834400-B2 | Method for synthesizing dibenzocycloheptane derivatives by series cyclization of free radicals under electrooxidation conditions | POR, CYP2E1, AKR7A2 | PAX8 4853/4885HPRT1 907/4885ALDH1A1 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.