Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114064 | 0.84 | MCHR1 (0.46) | MCHR1DRD2DRD3KCNH2NOTUM | |
| SCHEMBL5107708 | 0.79 | DRD2 (0.45) | MCHR1DRD2DRD3KCNH2NOTUM | |
| SCHEMBL5108414 | 0.75 | NOTUM (0.41) | MCHR1DRD2DRD3KCNH2NOTUM | |
| SCHEMBL7610426 | 0.75 | MCHR1 (0.45) | MCHR1DRD2DRD3KCNH2NOTUM | |
| SCHEMBL7609608 | 0.75 | MCHR1 (0.45) | MCHR1DRD2DRD3KCNH2NOTUM | |
| SCHEMBL8788931 | 0.73 | MCHR1 (0.44) | MCHR1DRD2DRD3KCNH2NOTUM | |
| SCHEMBL7608385 | 0.73 | NOTUM (0.52) | MCHR1DRD2DRD3KCNH2NOTUM | |
| SCHEMBL7609591 | 0.73 | NOTUM (0.52) | MCHR1DRD2DRD3KCNH2NOTUM | |
| SCHEMBL8788607 | 0.73 | DRD2 (0.50) | MCHR1DRD2DRD3KCNH2NOTUM | |
| SCHEMBL7604476 | 0.73 | NOTUM (0.52) | MCHR1DRD2DRD3KCNH2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355053-B2 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-08 | — | — | US | disclosed |
| US-20060019831-A1 | 1-phenylpyrrolidine-2-one-3-carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019831-A1 | 1-phenylpyrrolidine-2-one-3-carboxamides | RXFP1, REN, NPY1R | MCHR1 761/4885DRD2 156/4885DRD3 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.