Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604476 | 0.84 | NOTUM (0.52) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL7608385 | 0.84 | NOTUM (0.52) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8554695 | 0.84 | DRD2 (0.50) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL7609591 | 0.84 | NOTUM (0.52) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8787922 | 0.84 | DRD2 (0.50) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL8568624 | 0.82 | ROCK2 (0.56) | DRD2DRD3KCNH2MCHR1ROCK2 | |
| SCHEMBL8568619 | 0.82 | ROCK2 (0.56) | DRD2DRD3KCNH2MCHR1ROCK2 | |
| SCHEMBL9273396 | 0.82 | NOTUM (0.59) | DRD2DRD3KCNH2NOTUMMCHR1 | |
| SCHEMBL965009 | 0.81 | CA12 (0.54) | DRD2DRD3NOTUM | |
| SCHEMBL8563716 | 0.81 | CA12 (0.54) | DRD2DRD3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |