Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 8/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5094916 | 0.91 | GSK3B (0.44) | NPC1MAPTRAB9ACASP3CASP7 | |
| SCHEMBL5095099 | 0.86 | CNR2 (0.43) | NPC1MAPTRAB9ACNR2ABCB1 | |
| SCHEMBL5107927 | 0.85 | CNR2 (0.49) | NPC1MAPTRAB9ACNR2ABCB1 | |
| Hydrochloric Acid SCHEMBL5102076 | 0.85 | CNR2 (0.43) | NPC1MAPTRAB9ACNR2ABCB1 | |
| SCHEMBL5101554 | 0.85 | NPC1 (0.38) | NPC1MAPTRAB9ACNR2ABCB1 | |
| SCHEMBL5101622 | 0.83 | NPBWR1 (0.46) | NPC1MAPTRAB9ACASP3CASP7 | |
| SCHEMBL5094854 | 0.81 | GSK3B (0.41) | NPC1MAPTRAB9ACASP3CASP7 | |
| SCHEMBL5094797 | 0.81 | RAB9A (0.39) | NPC1MAPTRAB9ACASP3CASP7 | |
| SCHEMBL5108392 | 0.77 | GSK3B (0.44) | MAPTRAB9ACASP3CASP7 | |
| SCHEMBL5098172 | 0.77 | GSK3B (0.41) | MAPTCNR2KMT2AMEN1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314877-B2 | Benzofuran derivative | KOWA CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-20060189621-A1 | Benzofuran derivative | KOWA CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1602655-A1 | BENZOFURAN DERIVATIVE | Kowa Co., Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189621-A1 | Benzofuran derivative | TNF, TNFRSF1A, RELA | NPC1 337/4885MAPT 4749/4885RAB9A 4218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.