Guanidine

Guanidine

SCHEMBL5102

N=C(N)N.O=C(O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2

The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanidine SCHEMBL14677179 1.00 ACHE (0.55)
Guanidine SCHEMBL9661571 1.00 ACHE (0.55)
Guanidine SCHEMBL1319550 1.00 ACHE (0.55)
Guanidine SCHEMBL28378215 0.95 ACHE (0.50)
Guanidine SCHEMBL5696251 0.95
Guanidine SCHEMBL29215572 0.95
Guanidine SCHEMBL8573951 0.95 LMNA (0.55)
Guanidine SCHEMBL7757618 0.95
Guanidine SCHEMBL13581685 0.91 ACHE (0.46)
Benzene SCHEMBL27533838 0.91 ACHE (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13298 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071736-A Free DNA extraction kit, extraction method and application 武汉华大智造科技有限公司 2026-05-22 CN claimed
CN-117143592-B Mn (Mn)4+Activated fluoride (oxide) red fluorescent material and preparation method thereof 华南理工大学 2026-05-22 CN claimed
CN-122061359-A Double pH value alkali gradient utilization low-salt environment-friendly dyeing and finishing process 吕文祥 2026-05-19 CN claimed
US-12630526-B2 Processes for preparing aminopyrimidine compounds ARCUS BIOSCIENCES, INC. (US) 2026-05-19 US claimed
CN-122059785-A Method for preparing 1, 1-disubstituted alkene by rhodium-catalyzed decarboxylation cracking 华南理工大学 2026-05-19 CN claimed
CN-224236476-U Ammonia absorption tower with buffer structure for guanidine carbonate refining 南通天泽化工有限公司 2026-05-15 CN claimed
CN-122031662-A Application of gelatin and chaotropic agent in preparation of medicine for treating androgenetic alopecia 四川大学 2026-05-15 CN claimed
CN-122017076-A Method for detecting carbomer content in pharmaceutical preparation 浙江康恩贝制药股份有限公司 2026-05-12 CN claimed
CN-122028640-A Wide-temperature-range flexible ion thermoelectric battery and preparation method thereof 东南大学 2026-05-12 CN claimed
US-12616948-B2 Polyamide microcapsules FIRMENICH SA (CH) 2026-05-05 US claimed
US-4098972-A ANTISCALING AGENTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1978-07-04 US claimed
US-4075209-A Process for preparing substituted 2,4-diaminopyrimidines and isoxazole intermediate HOFFMANN-LA ROCHE, INC. (US) 1978-02-21 US claimed
US-4045399-A DICYANDIAMIDE OR A GUANIDINE SALT, SALT OF AN ACRYLIC ESTER-UNSATURATED ACID COPOLYMER TOYO INK MFG. CO., LTD. (JA) 1977-08-30 US claimed
US-4043987-A FLAME RETARDANTS ENCOAT CHEMICALS LIMITED (CA) 1977-08-23 US claimed
US-4008234-A Process for the preparation of melon CHEMIE LINZ AKTIENGESELLSCHAFT (OE) 1977-02-15 US claimed
US-4006048-A Reverse printed high-pressure laminates WESTINGHOUSE ELECTRIC CORPORATION (US) 1977-02-01 US claimed
US-3984471-A CONTAINING GUANIDINE, UREA, PYROLYSIS PRODUCTS OF UREA, AMMONIA AND CARBON DIOXIDE CHEMIE LINZ AKTIENGESELLSCHAFT (OE) 1976-10-05 US claimed
US-3956040-A Explosive slurry composition containing sodium montmorillonite GELAN KABUSHIKI KAISHA (JA) 1976-05-11 US claimed
US-3952057-A Process for the preparation of guanidine carbonate CHEMIE LINZ AG (OE) 1976-04-20 US claimed
US-3943954-A Pipeline transportation of viscous hydrocarbons TEXACO INC. (US) 1976-03-16 US claimed