Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL28378215 | 1.00 | ACHE (0.50) | — | |
| Guanidine SCHEMBL13581685 | 0.96 | ACHE (0.46) | — | |
| Guanidine SCHEMBL5102 | 0.95 | — | — | |
| Guanidine SCHEMBL14677179 | 0.95 | ACHE (0.55) | — | |
| Guanidine SCHEMBL1319550 | 0.95 | ACHE (0.55) | — | |
| Guanidine SCHEMBL9661571 | 0.95 | ACHE (0.55) | — | |
| Guanidine SCHEMBL29215572 | 0.91 | — | — | |
| Guanidine SCHEMBL8573951 | 0.91 | LMNA (0.55) | — | |
| Guanidine SCHEMBL5696251 | 0.91 | — | — | |
| Guanidine SCHEMBL28303749 | 0.87 | ACHE (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727477-B1 | Ash-free detergents, their preparation, and use in lubricating oil compositions | LUBRIZOL ADIBIS HOLDINGS LTD (GB) | 2001-03-14 | — | — | EP | disclosed |
| US-5780403-A | Ash-free detergents their preparation and use in lubricating oil compositions | BP CHEMICALS (ADDITIVES) LIMITED (GB) | 1998-07-14 | — | — | US | disclosed |
| EP-0727477-A2 | Ash-free detergents, their preparation, and use in lubricating oil compositions | BP CHEMICALS (ADDITIVES) LIMITED (GB) | 1996-08-21 | — | — | EP | disclosed |