Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058795 | 0.83 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5048171 | 0.81 | PNP (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5104179 | 0.80 | HPRT1 (0.35) | HPRT1 | |
| SCHEMBL6268075 | 0.79 | ADORA2A (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6265333 | 0.77 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7758685 | 0.76 | PDE4A (0.33) | HPRT1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6271387 | 0.75 | CDK1 (0.37) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6265529 | 0.74 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5503490 | 0.73 | ADORA2A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| Ethylene SCHEMBL6271500 | 0.72 | PDE4A (0.31) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977296-A | MONOMERS WITH ALIPHATIC CYCLIC STRUCTURE IN THE BACKBONE; FOR INCREASED CONFORMATION RESTRICTION LEADING TO INCREASED BINDING AFFINITY AND SPECIFICITY; FOR DETECTING POINT MUTATIONS, FOR SUPPRESSING WILD TYPE GENES IN AMPLIFICATION | NIELSEN, PETER E. (DK) | 1999-11-02 | — | — | US | disclosed |
| WO-1996020212-A2 | PEPTIDE NUCLEIC ACID INCORPORATING A CHIRAL BACKBONE | BUCHARDT, DORTE (DK) | 1996-07-04 | — | — | WO | disclosed |