Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030617 | 0.91 | ALDH1A1 (0.54) | ALDH1A1TDP1HSD17B10TSHRPTGS2 | |
| Benzoic Acid SCHEMBL27860650 | 0.86 | TSHR (0.52) | ALDH1A1TDP1TSHRPTGS2MAPK1 | |
| SCHEMBL27547128 | 0.76 | MAPT (0.41) | ALDH1A1TDP1HSD17B10TSHRALOX15 | |
| SCHEMBL27859456 | 0.76 | TGM2 (0.39) | ALDH1A1TDP1TSHRTP53SMN1; SMN2 | |
| SCHEMBL28313469 | 0.76 | CTSD (0.44) | ALDH1A1CTSDL3MBTL1EPHX1SMN1; SMN2 | |
| SCHEMBL11666650 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL28188600 | 0.76 | KMT2A (0.41) | ALDH1A1TDP1ALOX12LMNACYP2A6 | |
| SCHEMBL28173504 | 0.76 | HSD17B10 (0.41) | ALDH1A1HSD17B10TSHRPTGS2EPHX1 | |
| SCHEMBL2789858 | 0.75 | TGM2 (0.40) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL13402842 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TDP1HSD17B10CTSDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104109120-A | N'-aryl acryloyl o-pyridine hydrazide derivatives, and preparation methods, pharmaceutical composition and application thereof | INST MATERIA MEDICA CAMS | 2014-10-22 | — | — | CN | claimed |
| CN-102731413-A | Urea compound and its preparation method, intermediate and use | SHANGHAI INST PHARM INDUSTRY | 2012-10-17 | — | — | CN | claimed |
| US-6238754-B1 | MULTILAYER POLYIMIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-05-29 | — | — | US | claimed |
| CN-116617993-A | Device and method for preparing polymethylene polyphenyl polyurethane | 中国科学院过程工程研究所 | 2023-08-22 | — | — | CN | disclosed |
| CN-110506040-A | Kill the oxadiazole derivatives of microorganism | SYNGENTA PARTICIPATIONS AG | 2019-11-26 | — | — | CN | disclosed |
| CN-110392683-A | Kill the oxadiazole derivatives of microorganism | 先正达参股股份有限公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-110382492-A | Microbicidal oxadiazole derivatives | 先正达参股股份有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-105960402-B | Microbicidal heterobicyclic derivatives | 先正达参股股份有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-109923112-A | Kill the oxadiazole derivatives of microorganism | 先正达参股股份有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-109890209-A | Kill the oxadiazole derivatives of microorganism | 先正达参股股份有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109476614-A | Kill the oxadiazole derivatives of microorganism | 先正达参股股份有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-1028523-C | Process for preparing carbamic acid | SHELL INT RESEARCH (NL) | 1995-05-24 | — | — | CN | disclosed |
| CN-1045579-A | Process for preparing carbamates and intermediate thereof | SHELL INT RESEARCH (NL) | 1990-09-26 | — | — | CN | disclosed |
| US-4923504-A | 2-(2-Imidazolin-2-yl)pyridines and quinolines, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4798619-A | 2-(2-imidazolin-2-yl)-pyridines and quinolines and use of said compounds as herbicidal agents | AMERICAN CYANAMID CO. (US) | 1989-01-17 | — | — | US | disclosed |
| US-4638068-A | 2-(2-imidazolin-2-yl)-pyridines and quinolines, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0041623-B1 | SUBSTITUTED IMIDAZOLINYL NICOTINE ACIDS, ESTERS AND SALTS AND USE THEREOF AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| EP-0041624-B1 | METHOD TO BENEFICIALLY INFLUENCE & ALTER THE DEVELOPMENT & LIFE CYCLE OF AGRONOMIC AND HORTICULTURAL CROPS WITH CERTAIN IMIDAZOLINYL NICOTINIC ACIDS AND DERIVATIVES THEREOF | AMERICAN CYANAMID COMPANY (US) | 1984-02-01 | — | — | EP | disclosed |
| EP-0041623-A2 | Substituted imidazolinyl nicotine acids, esters and salts and use thereof as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1981-12-16 | — | — | EP | disclosed |
| EP-0041624-A2 | Method to beneficially influence & alter the development & life cycle of agronomic and horticultural crops with certain imidazolinyl nicotinic acids and derivatives thereof | AMERICAN CYANAMID COMPANY (US) | 1981-12-16 | — | — | EP | disclosed |