Urea

Urea

SCHEMBL510558

C/C=C/C(O)O.NC(N)=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
ALDH1A1 P00352 1/20 0.35
OR51E2 Q9H255 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL510560 1.00 LMNA (0.35) LMNAALDH1A1OR51E2TDP1ALOX15
SCHEMBL7696717 0.84
SCHEMBL306604 0.84
SCHEMBL465102 0.84
Pivalate SCHEMBL8849884 0.76 ALDH1A1 (0.35) ALDH1A1
Methacrylic Acid SCHEMBL6142596 0.74 TGFBR1 (0.32) TDP1
Urea SCHEMBL3384841 0.73
Urea SCHEMBL3384849 0.73
SCHEMBL13742840 0.71 LMNA (0.32) LMNAALOX15BLMPMP22
Urea SCHEMBL8865246 0.70 ALDH1A1 (0.30) LMNAALDH1A1OR51E2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9109200-B2 Use of enzymes to reduce aldehydes from aldehyde-containing products BASF SE (DE) 2015-08-18 US disclosed
EP-2417253-A1 USE OF ENZYMES TO REDUCE ALDEHYDES FROM ALDEHYDE-CONTAINING PRODUCTS BASF SE (DE) 2012-02-15 EP disclosed
US-20120028333-A1 USE OF ENZYMES TO REDUCE ALDEHYDES FROM ALDEHYDE-CONTAINING PRODUCTS BASF SE (DE) 2012-02-02 US disclosed
WO-2010115797-A1 USE OF ENZYMES TO REDUCE ALDEHYDES FROM ALDEHYDE-CONTAINING PRODUCTS BASF SE (DE) 2010-10-14 WO disclosed
EP-2239322-A1 Use of enzymes to reduce formaldehyde from formaldehyde-containing products BASF SE (DE) 2010-10-13 EP disclosed