Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.44 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.44 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.40 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PRKX | P51817 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | KLRK1 | P26718 | 7/20 | 0.40 |
| ▸ | MICA | Q29983 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781343 | 0.92 | POLB (0.49) | NPC1POLBALDH1A1TGFBR1ACVR1B | |
| SCHEMBL4394775 | 0.82 | NPC1 (0.56) | NPC1POLBALDH1A1MAPTKLRK1 | |
| SCHEMBL3762834 | 0.81 | ALDH1A1 (0.60) | NPC1POLBALDH1A1MAPTDGAT2 | |
| SCHEMBL6776473 | 0.80 | NPC1 (0.59) | NPC1POLBALDH1A1MAPTDGAT2 | |
| SCHEMBL15244373 | 0.80 | NPC1 (0.62) | NPC1POLBALDH1A1MAPTROCK2 | |
| SCHEMBL6781346 | 0.79 | NPC1 (0.49) | NPC1POLBALDH1A1MAPTMAPK1 | |
| SCHEMBL31446908 | 0.79 | NPC1 (0.49) | NPC1POLBALDH1A1MAPTKLRK1 | |
| SCHEMBL6081356 | 0.79 | NPC1 (0.61) | NPC1POLBALDH1A1MAPTROCK2 | |
| SCHEMBL21620525 | 0.78 | SIRT3 (0.51) | TGFBR1ACVR1BACVRL1ROCK2RPS6KA5 | |
| SCHEMBL29100719 | 0.78 | NPC1 (0.57) | NPC1POLBALDH1A1MAPTDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100408574-C | Nicotinic acid-heterocyclyl-amides and analogous pyrimidine derivatives serving as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2008-08-06 | — | — | CN | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1434485-B1 | NICOTINIC ACID-HETEROCYCLYL-AMIDES AND ANALOGOUS PYRIMIDINE DERIVATIVES FOR USE AS PESTICIDES | MERIAL LTD (US) | 2007-05-16 | — | — | EP | disclosed |
| EP-1434485-B1 | NICOTINIC ACID-HETEROCYCLYL-AMIDES AND ANALOGOUS PYRIMIDINE DERIVATIVES FOR USE AS PESTICIDES | MERIAL LTD (US) | 2007-05-16 | — | — | EP | disclosed |
| EP-1434485-A1 | NICOTINIC ACID-HETEROCYCLYL-AMIDES AND ANALOGOUS PYRIMIDINE DERIVATIVES SERVING AS PESTICIDES | Bayer CropScience GmbH (DE) | 2004-07-07 | — | — | EP | disclosed |
| US-20040006047-A1 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED | 2004-01-08 | — | — | US | disclosed |
| WO-2003028459-A1 | NICOTINIC ACID-HETEROCYCLYL-AMIDES AND ANALOGOUS PYRIMIDINE DERIVATIVES SERVING AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006047-A1 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | CBR1, HCN1, SCN1A | NPC1 782/4885POLB 4168/4885ALDH1A1 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.