Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX2 | Q96LB1 | 5/20 | 0.77 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459625 | 0.87 | MRGPRX2 (1.00) | MRGPRX2OPRM1OPRK1OPRD1ADRB1 | |
| SCHEMBL5108263 | 0.87 | MRGPRX2 (1.00) | MRGPRX2OPRM1OPRK1OPRD1ADRB1 | |
| Hydrochloric Acid SCHEMBL8168636 | 0.86 | MRGPRX2 (0.98) | MRGPRX2OPRM1OPRK1OPRD1ADRB1 | |
| SCHEMBL6157352 | 0.85 | MRGPRX2 (0.77) | MRGPRX2OPRM1OPRK1OPRD1ADRB1 | |
| SCHEMBL20522476 | 0.84 | MRGPRX2 (0.78) | MRGPRX2OPRM1OPRK1OPRD1ADRB1 | |
| SCHEMBL12143747 | 0.82 | MRGPRX2 (0.72) | MRGPRX2OPRM1OPRK1OPRD1ADRB1 | |
| SCHEMBL3013997 | 0.79 | MRGPRX2 (0.62) | MRGPRX2OPRM1OPRK1OPRD1 | |
| SCHEMBL4081399 | 0.79 | MRGPRX2 (0.68) | MRGPRX2OPRM1OPRK1OPRD1 | |
| SCHEMBL13250907 | 0.79 | OPRM1 (0.84) | MRGPRX2OPRM1OPRK1OPRD1ADRB1 | |
| SCHEMBL3019720 | 0.79 | MRGPRX2 (0.61) | MRGPRX2OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465797-B2 | 6-monoacetylmorphine derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-20070191595-A1 | 6-MONOACETYLMORPHINE DERIVATIVES USEFUL IN IMMUNOASSAY | GHOSHAL MITALI | 2007-08-16 | — | — | US | disclosed |
| EP-1810973-A1 | 6-monoacetylmorphine derivatives useful in immunoassay | Roche Diagnostics GmbH (DE) | 2007-07-25 | — | — | EP | disclosed |
| US-7238791-B1 | 6-monoacetylmorphine derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| US-20070142628-A1 | 6-Monoacetylmorphine derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191595-A1 | 6-MONOACETYLMORPHINE DERIVATIVES USEFUL IN IMMUNOASSAY | OPRM1, MAG, IL6ST | MRGPRX2 707/4885OPRM1 1/4885OPRK1 24/4885 |
| US-20070142628-A1 | 6-Monoacetylmorphine derivatives useful in immunoassay | OPRM1, MAG, IL6ST | MRGPRX2 707/4885OPRM1 1/4885OPRK1 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.