Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138332 | 0.91 | F10 (0.44) | F10CYP2C9 | |
| SCHEMBL1406028 | 0.87 | F10 (0.54) | F10 | |
| SCHEMBL1405985 | 0.87 | F10 (0.54) | F10 | |
| SCHEMBL14078392 | 0.87 | F10 (0.47) | F10CYP2C9ITGB1ITGA4 | |
| SCHEMBL1405894 | 0.79 | F10 (0.50) | F10 | |
| SCHEMBL1406097 | 0.78 | F10 (0.55) | F10 | |
| SCHEMBL1405846 | 0.78 | F10 (0.55) | F10 | |
| SCHEMBL1405891 | 0.78 | F10 (0.52) | F10 | |
| SCHEMBL4030148 | 0.76 | F10 (0.77) | F10 | |
| SCHEMBL4030144 | 0.76 | F10 (0.77) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427618-B2 | Ethynyl derivatives as factor Xa inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-23 | — | — | US | disclosed |
| US-7427618-B2 | Ethynyl derivatives as factor Xa inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-23 | — | — | US | disclosed |
| US-7427618-B2 | Ethynyl derivatives as factor Xa inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-23 | — | — | US | disclosed |
| US-20060084648-A1 | Ethynyl derivatives as factor xa inhibitors | MERCK PATENT GMBH (DE) | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084648-A1 | Ethynyl derivatives as factor xa inhibitors | F12, F11, SERPINC1 | F10 4/4885CYP2C9 257/4885CA12 2668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.