⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15233233 | 1.00 | — | — | |
| SCHEMBL512431 | 0.97 | IDO1 (0.50) | — | |
| SCHEMBL22165011 | 0.97 | IDO1 (0.50) | — | |
| SCHEMBL1835628 | 0.97 | IDO1 (0.50) | — | |
| SCHEMBL8015172 | 0.92 | MAOB (0.52) | — | |
| SCHEMBL8885029 | 0.85 | NFE2L2 (0.54) | — | |
| SCHEMBL6336359 | 0.85 | LTA4H (0.46) | — | |
| SCHEMBL8885030 | 0.85 | NFE2L2 (0.54) | — | |
| SCHEMBL3103451 | 0.85 | IDO1 (0.41) | — | |
| SCHEMBL18166888 | 0.83 | IDO1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7814 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | claimed |
| CN-121342670-B | N (N)1,N1,N2,N2-Tetra (4-fluorobenzyl) cyclohexane-1, 2-diamine and preparation method and application thereof | 辽宁华昇金玛生态工程有限公司 | 2026-02-27 | — | — | CN | claimed |
| US-12304917-B1 | Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-05-20 | — | — | US | claimed |
| CN-119874601-A | 3, 3-Dimethyl-1, 2,3, 4-tetrahydro-9H-carbazole derivative and preparation method and application thereof | 山东大学 | 2025-04-25 | — | — | CN | claimed |
| US-12275734-B1 | Pleuromutilin onium salt derivative containing a 3H-imidazo[4,5-c]pyridine side chain, and a preparation method and application thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-04-15 | — | — | US | claimed |
| CN-116375643-B | Deaconitine derivative and preparation method and application thereof | 中国人民解放军海军军医大学 | 2025-04-01 | — | — | CN | claimed |
| CN-119390627-A | Synthesis method of photocatalytic asymmetric thioether compound | 中国人民解放军军事科学院防化研究院 | 2025-02-07 | — | — | CN | claimed |
| CN-119101052-A | Matrine-triazole derivative and synthesis method thereof | 吉林医药学院 | 2024-12-10 | — | — | CN | claimed |
| EP-4452952-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) | 2024-10-30 | — | — | EP | claimed |
| CN-118546155-A | Pleuromutilin derivative containing thiazolo [5,4-C ] pyridine side chain and preparation method and application thereof | 西安康诺化工有限公司 | 2024-08-27 | — | — | CN | claimed |
| US-20140051673-A1 | AMPK-Activating Heterocycloalkyloxy(Hetero)Aryl Carboxamide, Sulfonamide And Amine Compounds And Methods For Using The Same | RIGEL PHARMACEUTICALS, INC. (US) | 2014-02-20 | — | — | US | claimed |
| US-20120115838-A1 | AMPK-Activating Heterocycloalkyloxy(Hetero)Aryl Carboxamide, Sulfonamide And Amine Compounds And Methods For Using The Same | RIGEL PHARMACEUTICALS, INC. (US) | 2012-05-10 | — | — | US | claimed |
| US-20100249321-A1 | Polymerisation of ethylenically unsaturated monomers | CRODA INTERNATIONAL PLC (GB) | 2010-09-30 | — | — | US | claimed |
| US-7759443-B2 | Polymerisation of ethylenically unsaturated monomers | Croda International, Inc. (GB) | 2010-07-20 | — | — | US | claimed |
| US-20090170829-A1 | Carboxamide, Sulfonamide and Amine Compounds and Methods for Using The Same | RIGEL PHARMACEUTICALS, INC. (US) | 2009-07-02 | — | — | US | claimed |
| US-20070037938-A1 | Using a catalyst system including: a manganese carbonyl radical initiator (dimanganese decacarbonyl); a halogen containing reactive substrate; and an allylic halogen substituted chain termination agent (2,3-dibromopropene) to produce telechelic polymers with narrow molecular weight distribution | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2007-02-15 | — | — | US | claimed |
| EP-1606323-A1 | POLYMERISATION OF ETHYLENICALLY UNSATURATED MONOMERS | Imperial Chemical Industries PLC (GB) | 2005-12-21 | — | — | EP | claimed |
| WO-2004085494-A1 | POLYMERISATION OF ETHYLENICALLY UNSATURATED MONOMERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2004-10-07 | — | — | WO | claimed |
| EP-0375005-B1 | Substituted thiophenes, conductive polymers derived from these thiophenes, process for their preparation and devices containing these polymers | SOLVAY (BE) | 1994-09-21 | — | — | EP | claimed |
| EP-0034741-B1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED BROMOFLUOROBENZENE AND 3-BROMO-4-FLUOROBENZONITRILE | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1983-12-21 | — | — | EP | claimed |