Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5110 | 0.97 | — | — | |
| SCHEMBL15233233 | 0.97 | — | — | |
| SCHEMBL22165011 | 0.94 | IDO1 (0.50) | IDO1LOXL2TRPA1ALDH1A1TSHR | |
| SCHEMBL1835628 | 0.94 | IDO1 (0.50) | IDO1LOXL2TRPA1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL26962946 | 0.94 | IDO1 (0.50) | IDO1LOXL2TRPA1ALDH1A1TSHR | |
| SCHEMBL8015172 | 0.89 | MAOB (0.52) | IDO1LOXL2TRPA1ALDH1A1TSHR | |
| Benzyl Bromide SCHEMBL28194850 | 0.87 | ALDH1A1 (0.70) | IDO1LOXL2TRPA1ALDH1A1TSHR | |
| SCHEMBL8885030 | 0.83 | NFE2L2 (0.54) | IDO1 | |
| SCHEMBL3103451 | 0.83 | IDO1 (0.41) | IDO1LOXL2TRPA1ALDH1A1TSHR | |
| SCHEMBL8885029 | 0.83 | NFE2L2 (0.54) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908996-A | A composition containing C (sp2) P bond or C (sp)3) Process for preparing organic phosphine compound of-P bond | 烟台大学 | 2024-11-08 | — | — | CN | claimed |
| WO-2002048133-A2 | A PROCESS FOR THE PREPARATION OF CITALOPRAM | C.D. FARMASINT S.R.L. (IT) | 2002-06-20 | — | — | WO | claimed |
| US-6384031-B1 | — | — | None | — | — | US | disclosed |
| US-6392040-B1 | — | — | None | — | — | US | disclosed |
| CN-118908996-A | A composition containing C (sp2) P bond or C (sp)3) Process for preparing organic phosphine compound of-P bond | 烟台大学 | 2024-11-08 | — | — | CN | disclosed |
| US-20240360124-A1 | Bromodomain Inhibitors | ABBVIE INC. (US) | 2024-10-31 | — | — | US | disclosed |
| CN-118184703-A | Synthesis method of alpha-substituted chiral phosphonate compound | 中国人民解放军军事科学院防化研究院 | 2024-06-14 | — | — | CN | disclosed |
| US-20220017511-A1 | Bromodomain Inhibitors | ABBVIE INC. (US) | 2022-01-20 | — | — | US | disclosed |
| CN-109071534-B | Bromodomain inhibitors | 艾伯维公司 | 2021-11-23 | — | — | CN | disclosed |
| US-20200255426-A1 | Bromodomain Inhibitors | ABBVIE INC. (US) | 2020-08-13 | — | — | US | disclosed |
| EP-3693369-A2 | BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-1027342-A1 | CYCLOPENTENE DERIVATIVES USEFUL AS ANTAGONISTS OF THE MOTILIN RECEPTOR | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5972939-A | Cyclopentene derivatives useful as antagonists of the motilin receptor | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1999021846-A1 | CYCLOPENTENE DERIVATIVES USEFUL AS ANTAGONISTS OF THE MOTILIN RECEPTOR | ORTHO-MCNEIL PHARMACEUTICAL INC. (US) | 1999-05-06 | — | — | WO | disclosed |
| US-5097047-A | Agricultural use, chemical intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5034052-A | Fungicides containing a triazole or imidazole alcohols, also used as plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-23 | — | — | US | disclosed |
| US-4990677-A | Fungicidal and plant growth-regulating azolylmethyl-cyclopropyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| US-4988819-A | 1,2,4-triazolemethyl ketones as chemical intermediates for plant growth regulators or fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4980488-A | Fungicidal and plant growth-regulating azolymethyl-cyclopropyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| US-4913727-A | Fungicidal and plant growth-regulating azolylmethyl-cyclopropyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017511-A1 | Bromodomain Inhibitors | BRD4, BRD3, BRD1 | IDO1 1434/4885LOXL2 4145/4885TRPA1 4350/4885 |
| US-20200255426-A1 | Bromodomain Inhibitors | BRD4, BRD3, BRD1 | IDO1 1434/4885LOXL2 4145/4885TRPA1 4350/4885 |
| US-20240360124-A1 | Bromodomain Inhibitors | BRD4, BRD3, BRD1 | IDO1 1434/4885LOXL2 4145/4885TRPA1 4350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.