Sugi Predict

Sugi Predict / Compounds / SCHEMBL5110175

SCHEMBL5110175

SCHEMBL5110175

CC(=O)c1ccc(-c2ccccc2NC(=O)c2c(C)nn(C)c2F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ POLB P06746 2/20 0.43
▸ MAPT P10636 2/20 0.43
▸ LMNA P02545 2/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ HTT P42858 4/20 0.42
▸ TSHR P16473 3/20 0.42
▸ HSD17B10 Q99714 2/20 0.42
▸ USP2 O75604 1/20 0.42
▸ KDM4E B2RXH2 2/20 0.39
▸ ATM Q13315 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ TNF P01375 1/20 0.38
▸ IL2 P60568 1/20 0.38
▸ STIM1 Q13586 1/20 0.38
▸ ORAI1 Q96D31 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13455819 0.90 ALDH1A1 (0.49) ALDH1A1KMT2AMEN1POLBMAPT
SCHEMBL11930691 0.90 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1POLBMAPT
SCHEMBL14266377 0.89 ALDH1A1 (0.43) ALDH1A1KMT2AMEN1POLBMAPT
SCHEMBL14266424 0.89 ALDH1A1 (0.43) ALDH1A1KMT2AMEN1POLBMAPT
SCHEMBL5111904 0.88 ALDH1A1 (0.42) ALDH1A1KMT2AMEN1POLBMAPT
SCHEMBL5111902 0.88 ALDH1A1 (0.42) ALDH1A1KMT2AMEN1POLBMAPT
SCHEMBL5110991 0.87 CYP1A2 (0.46) ALDH1A1KMT2APOLBMAPTLMNA
SCHEMBL13455934 0.86 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1POLBMAPT
SCHEMBL13455791 0.85 ALDH1A1 (0.45) ALDH1A1KMT2AMEN1POLBMAPT
SCHEMBL121859 0.85 ALDH1A1 (0.45) ALDH1A1KMT2AMEN1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7348350-B2 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms BAYER CROPSCIENCE AG (DE) 2008-03-25 — — US disclosed
US-6992098-B2 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms BAYER CROPSCIENCE AG (DE) 2006-01-31 — — US disclosed
US-20050182120-A1 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms ELBE HANS-LUDWIG (DE) 2005-08-18 — — US disclosed
US-20040053971-A1 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms BAYER CROPSCIENCE AG (DE) 2004-03-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040053971-A1 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms MRPL21, Q6ZSR9, MRM1 ALDH1A1 967/4885KMT2A 1141/4885MEN1 1530/4885
US-20050182120-A1 Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms DDT, MRPL21, DCXR ALDH1A1 948/4885KMT2A 784/4885MEN1 1903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.