Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3927970 | 0.90 | ALDH1A1 (0.48) | MAPTABCG2CYP3A4ABCB1NPC1 | |
| SCHEMBL3924860 | 0.80 | ESR1 (0.51) | ABCG2ABCB1NPC1ALDH1A1HPGD | |
| SCHEMBL1428881 | 0.80 | ESR1 (0.56) | MAPTABCG2CYP3A4ABCB1NPC1 | |
| SCHEMBL14266211 | 0.80 | MAOB (0.59) | MAPTABCG2CYP3A4ABCB1NPC1 | |
| SCHEMBL3224946 | 0.78 | PTGER1 (0.55) | NPC1MAOAMAOBRAB9AESR1 | |
| SCHEMBL5124786 | 0.78 | ALDH1A1 (0.49) | MAPTABCG2CYP3A4ABCB1NPC1 | |
| SCHEMBL5117226 | 0.78 | L3MBTL1 (0.44) | MAPTABCG2CYP3A4ABCB1NPC1 | |
| SCHEMBL3923936 | 0.77 | EGFR (0.51) | MAPTABCG2CYP3A4ABCB1NPC1 | |
| SCHEMBL8677842 | 0.76 | MAOA (0.58) | MAPTABCG2CYP3A4ABCB1NPC1 | |
| SCHEMBL3927806 | 0.76 | EGFR (0.46) | MAPTABCG2CYP3A4ABCB1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2959918-B1 | ANTI-MALIGNANT TUMOR AGENT COMPOSITION | J PHARMA CO LTD (JP) | 2019-05-22 | — | — | EP | disclosed |
| US-10172835-B2 | Anticancer agent composition | J-PHARMA CO., LTD. (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20160279103-A1 | AN ANTICANCER AGENT COMPOSITION | J-PHARMA CO., LTD. (JP) | 2016-09-29 | — | — | US | disclosed |
| EP-2959918-A1 | ANTI-MALIGNANT TUMOR AGENT COMPOSITION | J-Pharma Co., Ltd. (JP) | 2015-12-30 | — | — | EP | disclosed |
| EP-1481965-B1 | AROMATIC AMINO ACID DERIVATIVES AND MEDICINAL COMPOSITIONS | ENDO HITOSHI (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-7345068-B2 | Aromatic amino acid derivatives and medicinal compositions | Endou, Hitoshi (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20050119256-A1 | Aromatic amino acid derivates and medicinal compositions | HITOSHI ENDOU (JP) | 2005-06-02 | — | — | US | disclosed |
| EP-1481965-A1 | AROMATIC AMINO ACID DERIVATIVES AND MEDICINAL COMPOSITIONS | Endo, Hitoshi (JP) | 2004-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160279103-A1 | AN ANTICANCER AGENT COMPOSITION | TUBB1, TUBA1A, TUBA1C | MAPT 65/4885ABCG2 3578/4885CYP3A4 4448/4885 |
| US-20050119256-A1 | Aromatic amino acid derivates and medicinal compositions | SLC7A1, SLC1A5, SLC7A5 | MAPT 3710/4885ABCG2 805/4885CYP3A4 1469/4885 |
| US-10172835-B2 | Anticancer agent composition | TOP1, TUBB1, TUBA1A | MAPT 86/4885ABCG2 3184/4885CYP3A4 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.