Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 9/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217103 | 0.85 | LTA4H (0.50) | KDM4EKMT2A | |
| SCHEMBL5106764 | 0.83 | MAOB (0.44) | PSEN1ALOX5PTGESPPARGMAOB | |
| SCHEMBL5112726 | 0.82 | PPARG (0.47) | PSEN1ALOX5PTGESPPARGPPARD | |
| SCHEMBL5115379 | 0.79 | SCN9A (0.52) | PPARG | |
| SCHEMBL3211308 | 0.78 | CYP4F2 (0.49) | MAOBKDM4EKMT2A | |
| SCHEMBL5120231 | 0.77 | PSEN1 (0.43) | PSEN1ALOX5PTGESPPARGPPARD | |
| SCHEMBL3196887 | 0.76 | PPARG (0.70) | PPARG | |
| SCHEMBL5119936 | 0.76 | PSEN1 (0.44) | PSEN1ALOX5PTGESPPARGPPARD | |
| SCHEMBL18003392 | 0.76 | PTPRC (0.52) | PPARDMAOB | |
| SCHEMBL5110087 | 0.76 | NPSR1 (0.46) | PPARGHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | PSEN1 4026/4885ALOX5 672/4885PTGES 4106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.