Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.37 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100984 | 0.80 | HCAR1 (0.38) | ADH5RORCCYP2C9TTRALDH1A1 | |
| SCHEMBL8323009 | 0.72 | HSD17B10 (0.42) | CYP2C9PARP1ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL27635758 | 0.69 | TTR (0.47) | ADH5GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL3528958 | 0.67 | KDM4E (0.51) | ADH5RORCCYP2C9TTRCSF1R | |
| SCHEMBL6840252 | 0.67 | TTR (0.52) | RORCCYP2C9TTRKDM4E | |
| SCHEMBL3531980 | 0.66 | ADH5 (0.66) | ADH5CYP2C9ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL30220047 | 0.65 | DDB1 (0.44) | CYP2C9PARP1KDM4EALDH1A1HPGD | |
| SCHEMBL3526351 | 0.65 | TTR (0.59) | TTRKDM4EHSD17B10 | |
| SCHEMBL580653 | 0.64 | TTR (0.55) | TTRKDM4EALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL30991450 | 0.64 | PDE3B (0.47) | ADH5RORCCYP2C9TTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132496-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF, AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-06-05 | — | — | US | disclosed |
| US-7326791-B2 | Carboxylic acid amides, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO., KG (DE) | 2008-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132496-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF, AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | F12, F11, F2 | ADH5 354/4885GRIA1 1610/4885GRIA2 2184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.