Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 5/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5110128 | 0.90 | SENP5 (0.40) | SENP5SENP2SENP1KMT2AMEN1 | |
| SCHEMBL5110890 | 0.89 | SENP5 (0.40) | SENP5SENP2SENP1KMT2AMEN1 | |
| SCHEMBL5110065 | 0.89 | SENP5 (0.40) | SENP5SENP2SENP1KMT2AMEN1 | |
| SCHEMBL5116634 | 0.89 | BRD4 (0.39) | SENP5SENP2SENP1KMT2AMEN1 | |
| SCHEMBL4930828 | 0.89 | SMN1; SMN2 (0.39) | KMT2AMEN1SMN1; SMN2DHODHMAPT | |
| SCHEMBL5111593 | 0.87 | THRA (0.42) | SENP5SENP2SENP1KMT2AMEN1 | |
| SCHEMBL5116889 | 0.87 | SMN1; SMN2 (0.40) | SENP5SENP2SENP1KMT2AMEN1 | |
| SCHEMBL4932258 | 0.86 | SMN1; SMN2 (0.43) | KMT2AMEN1SMN1; SMN2DHODHMAPT | |
| SCHEMBL4350209 | 0.86 | SENP5 (0.52) | SENP5SENP2SENP1KMT2AMEN1 | |
| SCHEMBL5722494 | 0.86 | THRA (0.42) | SENP5SENP2SENP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | KARO BIO AB (SE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | TSHR, TRHR, THRA | SENP5 2379/4885SENP2 4509/4885SENP1 4088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.