SCHEMBL5111421

SCHEMBL5111421

COCc1[c]ccc(C)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.31
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27603316 0.98 ACHE (0.30) ACHE
SCHEMBL17818217 0.78 ACHE (0.33) ACHE
SCHEMBL11417292 0.78 ACHE (0.33) ACHE
SCHEMBL27791506 0.78 MAOB (0.31)
SCHEMBL27828699 0.78 POLB (0.32)
SCHEMBL28725283 0.78 IDO1 (0.35) ACHEIDO1
SCHEMBL195811 0.78 S1PR4 (0.33)
SCHEMBL9401075 0.76 IDH1 (0.41)
SCHEMBL215511 0.76
SCHEMBL9743951 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7361687-B2 Arylsulphonamide derivatives and methods of preparing LABORATOIRES FOURNIER SA (FR) 2008-04-22 US claimed
US-20060084699-A1 Novel arylsulphonamide derivatives and use thereof as therapeutic agents LABORATOIRES FOURNIER SA (FR) 2006-04-20 US claimed
CN-100417656-C Novel Bi compound, its prepn. method and process for prepn. of films TOSOH CORP (JP) 2008-09-10 CN disclosed
US-6916944-B2 Bismuth compound, process of producing the same, and process of producing a film TOSOH CORPORATION (JP) 2005-07-12 US disclosed
CN-1539841-A Novel Bi compound, its prepn. method and process for prepn. of films ������������ʽ���� 2004-10-27 CN disclosed
US-20040204483-A1 Novel bismuth compound, process of producing the same, and process of producing a film TOSOH CORPORATION 2004-10-14 US disclosed
EP-1466918-A1 Novel bismuth compounds, process of producing the same, and process of producing a film Tosoh Corporation (JP) 2004-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060084699-A1 Novel arylsulphonamide derivatives and use thereof as therapeutic agents UGT1A1, UGT2B7, UGT1A6 ACHE 4862/4885IDO1 2445/4885
US-20040204483-A1 Novel bismuth compound, process of producing the same, and process of producing a film APOB, RNF4, SUV39H1 ACHE 4369/4885IDO1 3415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.