SCHEMBL5111601

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5111591	0.90	P2RX7 (1.00)	P2RX7ELANECHRM2CHRM4CHRM5
	SCHEMBL4884041	0.82	P2RX7 (0.57)	P2RX7ELANEDYRK1AMALT1
	SCHEMBL5221250	0.81	P2RX7 (0.56)	P2RX7ELANEDYRK1AMALT1CYP3A4
	SCHEMBL5119633	0.81	P2RX7 (0.84)	P2RX7CHRM4CHRM5CHRM1CHRM3
	SCHEMBL5120174	0.76	CHRM1 (0.59)	P2RX7CHRM2CHRM4CHRM5CHRM1
	SCHEMBL5118323	0.76	P2RX7 (0.75)	P2RX7
	SCHEMBL5110946	0.74	P2RX7 (0.70)	P2RX7ELANEDYRK1AMALT1CYP3A4
	SCHEMBL1727773	0.73	P2RX7 (0.54)	P2RX7MALT1
	SCHEMBL4881090	0.72	P2RX7 (0.70)	P2RX7
	SCHEMBL1727778	0.72	P2RX7 (0.53)	P2RX7CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.