Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | CKS1B | P61024 | 11/20 | 0.49 |
| ▸ | SKP1 | P63208 | 11/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 11/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727778 | 0.91 | P2RX7 (0.53) | P2RX7CKS1BSKP1SKP2LDHA | |
| SCHEMBL1730153 | 0.88 | CHRM4 (0.52) | P2RX7LRRK2MALT1HTR1ADRD2 | |
| SCHEMBL3265694 | 0.84 | P2RX7 (0.47) | P2RX7CKS1BSKP1SKP2LRRK2 | |
| SCHEMBL1728655 | 0.83 | MALT1 (0.45) | P2RX7CKS1BSKP1SKP2LDHA | |
| SCHEMBL1727869 | 0.82 | KDM4E (0.62) | P2RX7LDHAMALT1DRD2 | |
| SCHEMBL1727561 | 0.81 | KMT2A (0.48) | P2RX7CKS1BSKP1SKP2MALT1 | |
| SCHEMBL1728967 | 0.80 | NSD2 (0.47) | P2RX7CKS1BSKP1SKP2HTR1A | |
| SCHEMBL1728699 | 0.80 | HRH4 (0.51) | CKS1BSKP1SKP2MALT1 | |
| SCHEMBL22776419 | 0.79 | ALDH1A1 (0.52) | CKS1BSKP1SKP2HTR1ADRD2 | |
| SCHEMBL3265672 | 0.76 | CHRM4 (0.45) | P2RX7LRRK2HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |