Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14924193 | 0.88 | HTR2A (0.54) | HTR2AHTR2CSLC6A4CNR1ACHE | |
| SCHEMBL631596 | 0.84 | HPGD (0.50) | HTR2AHTR2CSLC6A4LMNAHPGD | |
| SCHEMBL20488594 | 0.84 | SMN1; SMN2 (0.54) | CYP1A2SMN1; SMN2BRD4GAAMAPT | |
| SCHEMBL5120984 | 0.84 | SMN1; SMN2 (0.46) | HTR2AHTR2CSLC6A4HPGDCYP1A2 | |
| SCHEMBL28339416 | 0.83 | GRN (0.59) | CYP1A2SMN1; SMN2BRD4GAAMAPT | |
| SCHEMBL22054628 | 0.81 | GAA (0.59) | HPGDCYP1A2SMN1; SMN2PTGER1ALDH1A1 | |
| SCHEMBL5113571 | 0.81 | HPGD (0.47) | HTR2AHTR2CSLC6A4LMNAHPGD | |
| SCHEMBL24423881 | 0.80 | SMN1; SMN2 (0.50) | HPGDCYP1A2SMN1; SMN2BRD4ALDH1A1 | |
| SCHEMBL15056504 | 0.80 | SMN1; SMN2 (0.43) | CYP1A2SMN1; SMN2BRD4ALDH1A1GAA | |
| SCHEMBL13373542 | 0.80 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | HTR2A 2880/4885HTR2C 2477/4885SLC6A4 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.