⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437055 | 1.00 | — | — | |
| SCHEMBL5197140 | 1.00 | — | — | |
| SCHEMBL4233769 | 0.87 | — | — | |
| SCHEMBL6939465 | 0.86 | LMNA (0.38) | — | |
| Hydrochloric Acid SCHEMBL10822892 | 0.84 | CA12 (0.50) | — | |
| SCHEMBL2840047 | 0.84 | — | — | |
| SCHEMBL4284738 | 0.81 | CA2 (0.39) | — | |
| SCHEMBL4284741 | 0.81 | CNR1 (0.41) | — | |
| SCHEMBL5943150 | 0.81 | CERT1 (0.36) | — | |
| SCHEMBL48989 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199588-A1 | Chiral TACN/NOTA compounds/derivatives with and without metals for application | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2024-06-20 | — | — | US | disclosed |
| US-20230219975-A1 | PYRIDO[2,3-B][1,4]OXAZINES OR TETRAHYDROPYRIDO[2,3-B][1,4]OXAZEPINES AS IAP ANTAGONISTS | BEONE MEDICINES I GMBH (CH) | 2023-07-13 | — | — | US | disclosed |
| EP-3317277-B1 | SOMATOSTATIN MODULATORS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2021-01-20 | — | — | EP | disclosed |
| US-9957267-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170002001-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2017-01-05 | — | — | US | disclosed |
| US-20150166523-A1 | BRANCHED CHAIN ALKYL HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-06-18 | — | — | US | disclosed |
| EP-2862855-A1 | BRANCHED CHAIN ALKYL HETEROAROMATIC RING DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2015-04-22 | — | — | EP | disclosed |
| US-8420694-B2 | Pyrrolidin-2-one derivatives as androgen receptor modulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-04-16 | — | — | US | disclosed |
| EP-2176220-B1 | Pyrrolidin-2-one derivatives as androgen receptor modulators | TAKEDA PHARMACEUTICAL (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-7365075-B2 | Aryl sulfonamide compounds and uses related thereto | AMGEN INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-20050277649-A1 | Aryl sulfonamide compounds and uses related thereto | AMGEN SF, LLC (US) | 2005-12-15 | — | — | US | disclosed |