Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 13/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113072 | 1.00 | LIPE (0.54) | LIPEPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL2394885 | 0.83 | PTGER4 (0.62) | PTGER1PTGER4PTGER3PTGER2HDAC8 | |
| SCHEMBL2394889 | 0.83 | PTGER4 (0.62) | PTGER1PTGER4PTGER3PTGER2HDAC8 | |
| SCHEMBL5112014 | 0.80 | SCN9A (0.49) | SCN9ASCN10A | |
| SCHEMBL5112029 | 0.80 | SCN9A (0.49) | SCN9ASCN10A | |
| SCHEMBL7909151 | 0.79 | PTGER3 (0.68) | PTGER1PTGER4PTGER3PTGER2HDAC8 | |
| SCHEMBL7191225 | 0.79 | PTGER3 (0.68) | PTGER1PTGER4PTGER3PTGER2HDAC8 | |
| SCHEMBL13506000 | 0.76 | HPGD (0.71) | LIPEMRGPRX4PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL6035015 | 0.76 | HDAC8 (0.80) | PTGER1PTGER4PTGER3PTGER2HDAC8 | |
| SCHEMBL6035013 | 0.76 | HDAC8 (0.80) | PTGER1PTGER4PTGER3PTGER2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | LIPE 2122/4885PTGER1 2697/4885PTGER4 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.