Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | IDH2 | P48735 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5113759 | 0.93 | KCNMA1 (0.45) | AKR1C3AKR1C2IDH2NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5103755 | 0.90 | FFAR4 (0.44) | AKR1C3AKR1C2IDH2NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5113233 | 0.89 | FABP4 (0.46) | AKR1C3AKR1C2IDH2PDK1PDK2 | |
| Trifluoroacetic Acid SCHEMBL5099217 | 0.88 | AKR1C3 (0.41) | AKR1C3AKR1C2IDH2PDK1PDK2 | |
| Trifluoroacetic Acid SCHEMBL5099269 | 0.87 | AKR1C3 (0.44) | AKR1C3AKR1C2IDH2PDK2NPC1 | |
| Trifluoroacetic Acid SCHEMBL5099983 | 0.86 | RAB9A (0.39) | AKR1C3AKR1C2IDH2NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5103685 | 0.84 | MEN1 (0.44) | IDH2PDK1PDK2PDK3PDK4 | |
| Trifluoroacetic Acid SCHEMBL5113229 | 0.84 | IDH2 (0.44) | AKR1C3AKR1C2IDH2NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5107023 | 0.83 | IDH2 (0.45) | IDH2PDK1PDK2PDK3PDK4 | |
| SCHEMBL3906980 | 0.82 | HDAC7 (0.53) | NPC1RAB9AMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | LAINE DRAMANE I | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRNG, CHRM2 | AKR1C3 1908/4885AKR1C2 2538/4885IDH2 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.