SCHEMBL5113281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8981857	0.85	CHRM3 (0.53)	CHRM3SLC22A12ADRA2CNPSR1
	SCHEMBL6164465	0.84	LMNA (0.64)	CHRM3LMNAALDH1A1MEN1HPGD
	SCHEMBL10344931	0.83	PTGDR2 (0.58)	CHRM3XDHSLC22A12HTTLMNA
	SCHEMBL16438665	0.83	CHRM3 (0.45)	CHRM3XDHSLC22A12PTGDR2F11
	SCHEMBL6164487	0.83	MAPT (0.62)	CHRM3HTTLMNAALDH1A1MAPT
	SCHEMBL9551853	0.83	CHRM3 (0.48)	CHRM3SLC22A12HTTALDH1A1POLB
	SCHEMBL6164394	0.82	MAPT (0.64)	CHRM3HTTLMNAALDH1A1POLB
	SCHEMBL17796962	0.82	PTGDR2 (0.49)	HTTLMNAPTGDR2ALDH1A1POLB
	SCHEMBL265014	0.79	ALDH1A1 (0.62)	HTTALDH1A1POLBMAPTMEN1
	SCHEMBL16438561	0.78	CHRM3 (0.49)	CHRM3HTTLMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.