Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 7/20 | 0.58 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.56 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.46 |
| ▸ | IDH2 | P48735 | 3/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5113233 | 0.89 | FABP4 (0.46) | FABP4FABP5SHMT1IDH2LMNA | |
| Trifluoroacetic Acid SCHEMBL5112454 | 0.89 | FABP4 (0.44) | FABP4FABP5SHMT1IDH2NTRK1 | |
| Trifluoroacetic Acid SCHEMBL5100417 | 0.87 | FABP4 (0.45) | FABP4FABP5IDH2 | |
| Trifluoroacetic Acid SCHEMBL5103314 | 0.86 | IDH2 (0.44) | FABP4FABP5SHMT1IDH2GRIK1 | |
| Trifluoroacetic Acid SCHEMBL5103915 | 0.86 | FABP4 (0.44) | FABP4FABP5SHMT1IDH2LMNA | |
| Trifluoroacetic Acid SCHEMBL5113759 | 0.85 | KCNMA1 (0.45) | FABP4FABP5IDH2KCNMA1LMNA | |
| Trifluoroacetic Acid SCHEMBL5112036 | 0.83 | IDH2 (0.45) | FABP4FABP5SHMT1IDH2CNR1 | |
| Trifluoroacetic Acid SCHEMBL3912445 | 0.83 | CHRM3 (0.45) | FABP4FABP5IDH2CNR1 | |
| Trifluoroacetic Acid SCHEMBL5103755 | 0.82 | FFAR4 (0.44) | FABP4FABP5IDH2LMNASMN1; SMN2 | |
| SCHEMBL17797031 | 0.81 | FABP4 (0.64) | FABP4FABP5SHMT1GRIK1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | LAINE DRAMANE I | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249127-A1 | Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRNG, CHRM2 | FABP4 4255/4885FABP5 1382/4885SHMT1 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.