⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115144 | 0.90 | BDKRB1 (0.33) | — | |
| SCHEMBL5114486 | 0.86 | BDKRB1 (0.39) | — | |
| SCHEMBL5125505 | 0.86 | BDKRB1 (0.33) | — | |
| SCHEMBL5111226 | 0.84 | KMT2A (0.32) | — | |
| SCHEMBL5114574 | 0.84 | — | — | |
| SCHEMBL5110428 | 0.83 | LMNA (0.40) | — | |
| SCHEMBL5118238 | 0.83 | BDKRB1 (0.37) | — | |
| SCHEMBL5114552 | 0.83 | LMNA (0.32) | — | |
| SCHEMBL5118027 | 0.83 | BDKRB1 (0.35) | — | |
| SCHEMBL5118651 | 0.83 | HSD11B1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361687-B2 | Arylsulphonamide derivatives and methods of preparing | LABORATOIRES FOURNIER SA (FR) | 2008-04-22 | — | — | US | disclosed |
| US-20060084699-A1 | Novel arylsulphonamide derivatives and use thereof as therapeutic agents | LABORATOIRES FOURNIER SA (FR) | 2006-04-20 | — | — | US | disclosed |